Pulmonary Flashcards
definition: inversely proportional to the hydrogen ion concentration in blood
pH
definition: measures effectiveness of ventilation
pCO2 (partial pressure of CO2)
What is the inverse to pH?
pCO2
definition: measure of metabolic acid-base function
HCO3
definition: represents status of alveolar gas exchange
paO2
definition: percentage of hemoglobin saturation with oxygen
O2 sat
What is the normal pH level?
7.35-7.45
What is the normal pCO2 level?
35-45 mmHg
What is the normal HCO3 level?
22-26 mEq/L
What is the normal paO2 level?
80-100 mmHg
What are the panic levels for pH?
< 7.2
> 7.6
What are the panic levels for pCO2?
< 20
> 70
What are the panic levels for HCO3?
< 10
> 40
What is the panic level of pO2?
< 40
What is the panic level for O2?
< 60-70
What are the causes of respiratory acidosis?
- damage to the medulla
- airway obstruction
- loss of lung surface ventilation
- weak respiratory muscles
- overdose of respiratory depressants
What is the respiration center of the brain?
medulla
What are the s/s associated with respiratory acidosis?
- HYPOventilation
- confusion
- fatigue
- LOC
- diaphoresis
- shallow, rapid breathing
- restlessness
- cyanosis
What are the causes of respiratory alkalosis?
- HYPERventilation
- hyperthyroidism
- overventilation via mechanical ventilator
What are the s/s associated with respiratory alkalosis?
- hyperventilation
- lightheaded
- dizziness
- N/T of the face, fingers, and toes
- fainting/syncope
- convulsions
- arrythmias
What are the 4 items on the pulmonary checklist?
- dyspnea
- cough
- clubbing of the nails
- wheezing/stridor
definition: high-pitched noise caused by a partial obstruction of the airway
wheezing
definition: high-pitched sound associated w/ obstruction of the larynx or trachea
stridor
How can wheezing be resolved?
- opening the airway
- narrowing the airway
What are the primary pulmonary pain patterns?
- substernal/chest region over the involved lung
- side or back
What are the secondary pain patterns that radiate with pulmonary diseases?
neck, upper trap, costal margins, t-spine, scapula/shoulder
definition: Pain that refers to neck/ant chest (same level as irritation)
tracheobronchial
Explain what pleural pain feels like.
sharp and localized that is aggravated with any respiratory movement
What eases pleuritic pain?
auto-splinting –> tucking in the arm and laying on the affected side
Where is peripheral diaphragmatic pleural pain found?
costal margins and lumbar spine
Where is central diaphragmatic pleural pain found?
ipsilateral upper trap/shoulder
What kind of lung disease is CF?
genetic
What are blue bloaters?
chronic primary bronchitis
What is bronchitis?
inflammation of the trachea and bronchi
What are pink puffers?
emphysema
What is emphysema?
loss of elasticity or over distention
What can cause acute bronchitis?
chemical irritation or infection
What is a complication of acute bronchitis?
pneumonia
What causes chronic bronchitis?
prolonged exposure to irritants
What are complications of chronic bronchitis?
respiratory infection and lung disease
What are the s/s associated with bronchitis?
- wheezing
- dyspnea
- prolonged expiration
- obesity
- cyanosis and cor pumonale consisting of LE edema, elevated jugular venous pressure, R ventricular pressure, and tricuspid insufficiency
What is bronchiectasis?
cyclical bacterial infection that is followed by bronchial wall damage
When does bronchiectasis occur?
After infections (example: childhood pneumonia or CF)
What is a type of bronchitis that is a progressive and chronic pulmonary condition?
bronchiectasis
What are s/s associated with bronchiectasis?
- chronic wet cough with foul-smelling secretions
- worse in the morning
- bloody sputum (hemoptysis)
- sinusitis
- occasional wheezing
(true/false) Emphysema is not permanent.
FALSE (it is)
What are the s/s associated with emphysema?
- SOB; DOE
- Orthopnea (only able to breathe in upright position) after assuming supine position
- Barrel chest
- Minimally productive cough
- Pursed-lip breathing; use of accessory mm
- Prolonged expirations (often w/ grunt)
- Peripheral cyanosis
- Thin appearance
- Wheezing
- Diminished breath sounds
What are the two components of asthma?
allergen sensitization and inflammation
What are the types of asthma?
conventional, occupational, EIA
What is the cause of asthma?
Genetic disposition and environmental influences
definition: Inflammation of the lungs in response to the offending organism or agent
pneumonia
What are causes of pneumonia?
- Aspiration of food, fluids, or vomit
- Inhalation of toxic/caustic chemicals, dust, or gas
- Bacterial, viral, or mycoplasmal infection
What are risk factors for pneumonia?
- severe cold
- alcoholism
- disease
- poor health
What are red flags for pneumonia?
- pleuritis pain
- recent UTI
- confusion
- fever/chills/HA/malaise
- nausea
- productive cough (rust-colored or green, purulent sputum)
What is mediastinitis?
Swelling and irritation/inflammation of the area between the lungs (mediastinum)
What are s/s associated with mediastinitis?
- chest pain
- chills
- coughing up blood
- fever
- malaise
- SOB
How long can TB take to develop symptoms after initial infection?
3-10 weeks
What are the s/s associated with TB?
- Fatigue/Malaise
- Anorexia
- Wt loss
- Low-grade fever
- Night sweats
- Frequent productive cough
- Chest pain
- Dyspnea
What is scleroderma?
inflammation and fibrosis of many organs
What condition has the appearance of taut and shiny skin and atrophy of the webbed space?
scleroderma
What is the secondary site for scleroderma?
lung
What is the primary visceral site for scleroderma?
esophagus
What are the s/s associated with scleroderma?
- DOE
- Nonproductive cough
- Peripheral edema (secondary to cor pulmonale)
- Orthopnea
- Paroxysmal nocturnal dyspnea (CHF)
- Hemoptysis (coughing up blood)
- Sclerodactyly (hardening/shrinking of connective tissue of fingers/toes)
definition: Malignancy in the epithelium of the respiratory tract (12+ different types)
bronchiogenic carcinoma
Where are the METS normally found with bronchogenic carcinoma?
long bones, t-spine, liver, adrenal glands
(true/false) lung cancer cannot cross between the lungs or lobes of lungs.
true
(true/false) Low fruit/vegetable consumption is considered as a risk factor for lung cancer
true
What are the s/s associated with lung cancer?
- Change in respiratory patterns
- Recurrent pneumonia or bronchitis
- Hemoptysis
- Persistent cough
- Hoarseness/dysphagia
- Fecal breath odor
- classic Red Flags for CA
Cystic fibrosis is an inherited disease of the ________ that primarily affects what systems?
disease of exocrine glands that primarily affects the digestive and respiratory systems
What makes mucus abnormally thick and sticky in cases of cystic fibrosis?
Accumulation of salt in the cell lining of the lungs and digestive tissues
What is cystic fibrosis named after?
Named b/c of the cysts & scarring observed on the pancreas (secondary characteristic)
Where is the cystic fibrosis gene found?
chromosome 7
How does cystic fibrosis affect the GI system?
causes malnutrition which decreases absorption of the nutrients received
What are s/s associated with cystic fibrosis?
- Salty skin/sweat
- Recurrent pneumonia
- Persistent cough & wheezing
- Poor wt gain (despite excessive appetite)
- Bulky, foul-smelling stools (undigested fats)
definition: Rare CA of the pleura related to asbestos exposure
mesothelioma
(true/false) Mesothelioma is related to smoking.
FALSE (it is not)
definition: Scarring of lung tissue secondary to inhalation of strong, fine asbestos fibers
asbestosis
What is “Brown lung disease”?
Byssinosis
What is the cause of byssinosis?
Dust from hemp, flax, and cotton processing
What population is at risk for developing byssinosis?
textile workers
“Allergic alveolitis”, “Farmers Lung”, “Bird-Handlers Lung”
hypersensitivity pneumonitis
What is the cause of hypersensitivity pneumonitis?
Inhalation of organic antigens of fungal, bacterial or animal origin
“Dust diseases”
pneumoconioses
Pneumoconioses develops (gradually, rapidly)
gradually
What are Miners, construction workers, sandblasters, potters, and foundry/quarry workers most susceptible to forming?
pneumoconioses
Where is the location of pain for a PE?
substernal (but can be anywhere in thorax), shoulder, or upper abdominal
What are s/s associated with PE?
- Crushing chest pain
- dyspnea
- wheezing
- marked dec in BP
What are red flags and s/s for PE?
- chest, shoulder, or upper abdominal pain
- dyspnea
- PMH or risk factors for DVT
- tachypnea
- tachycardia
- Fever (103.5oF)
- Pleuritic chest pain
- Diffuse chest discomfort
- Persistent cough
- Hemoptysis
- Apprehension, anxiety, restlessness
Cor pulmonale affects the ____ side of the heart.
Right side
(true/false) Cor pulmonale is not a serious cardiac condition
FALSE
When does cor pulmonale occur?
when a massive PE obstructs 60-75% of the pulmonary circulation
Cor pulmonale is fostered by what?
Fostered by long-term pulmonary hypertension (arteries and right ventricle of the heart)
What is pulmonary artery hypertension?
High blood pressure in the arteries that supply the lungs
Vasoconstriction of the pulmonary arterial vascular bed can lead to _______.
endocarditis
What are the causes of pulmonary artery hypertension?
- PE
- Chronic lung disease
- polycythemia
- heart abnormalities
What is pleurisy?
inflammation of the pleura
What are red flags for pleurisy?
- Severe, sharp “knife-like” pain with inspiration
- History of a recent/co-existing respiratory disorder
- Dyspnea
Spontaneous pneumothorax is usually associated with what?
Ruptured lung wall
When does spontaneous pneumothorax resolve?
Within a few days if small
Aspiration if large
What usually causes a tension pneumothorax?
trauma
What type of pneumothorax is a medical emergency?
tension pneumothorax
Presentation:
- Severe “pleuritic-type” chest wall pain
- extreme SOB
- tracheal deviation (away from the involved side)
- distended neck veins
- tachycardia
- hypotension
- hyperresonance
tension pneumothorax
What are red flags for possible pneumothorax?
Chest pain - intensified with inspiration
Difficult to ventilate/expand ribcage
Hyperresonance upon percussion
Decreased breath sounds
What position worsens pulmonary symptoms?
recumbent
What are the 3 P’s to rule out pulmonary involvement?
- no pleuritic pain
- palpation tenderness
- pain with position changes (except recumbency)
When is shoulder pain caused by a pulmonary origin?
- agg with respiratory movements
- worsened with supine and recumbent positioning
- subsides with auto-splinting
(true/false) Pneumonia or heart failure are often the final event that starts a downward spiral of pulmonary failure leading to failure of other organ systems
true