Pulmo. Hypox/ch.cough/acu+ch bronch/UACS 10-28 (1) Flashcards
Hypoxemia.
Reduced PiO2 examples?
High altitude
Hypoxemia.
PiO2 A-a gradient?
normal
Hypoxemia.
Reduced PiO2 corrects with supplemental O2?
yes
Hypoxemia.
Hypoventilation examples?
CNS depression, morbid obesity, neuromuscular weakness
Hypoxemia.
Hypoventilation A-a gradient?
normal
Hypoxemia.
Hypoventilation corrects with supplemental O2?
yes
Hypoxemia.
Diffusion limitation examples?
Emphysema, ILD
Hypoxemia.
Diffusion limitation A-a gradient?
Increased
Hypoxemia.
Diffusion limitation corrects with supplemental O2?
yes
Hypoxemia.
V/Q mismatch*
examples?
*caused by localized dead-space ventilation and/or intrapulmonary shunting.
Small PE, lobar pneumonia
Hypoxemia.
V/Q mismatch A-a gradient?
Increased
Hypoxemia.
V/Q mismatch corrects with supplemental O2?
Yes
Hypoxemia.
Large intrapulmonary shunt examples?
Diffuse pulmonary edema
+ atelectasis, pneumonia
Hypoxemia.
Large intrapulmonary shunt A-a gradient?
Increased
Hypoxemia.
Large intrapulmonary shunt corrects with supplemental O2?
No
Hypoxemia.
Large dead space ventilation examples?
Massive PE, right-to-left intracardiac shunt
Hypoxemia.
Large dead space ventilation A-a gradient?
Increased
Hypoxemia.
Large dead space ventilation corrects with supplemental O2?
No
Hypoxemia. Intracardiac shunt (right to left), examples?
Tetralogy of Fallot, Eisenmenger syndrome
Hypoxemia. Intracardiac shunt (right to left), A-a gradient?
Increased
Hypoxemia. Intracardiac shunt (right to left), corrects with supplemental O2?
No
Chronic cough. Duration in adults and children?
> 8 weeks in adults and >4 weeks in children
Chronic cough.
Most common causes. Upper airway disorders? 2
Upper airways cough syndrome (UACS) (postnasal drip) - Allergic rhinitis, Nonallergic rhinitis (vasomotor), Acute nasopharyngitis, Sinusitis.
Chronic sinusitis
Chronic cough.
Most common causes. Lower airway and parenchymal disorders?
Asthma
Post respiratory tract infection
Chronic bronchitis
Bronchiectasis
Lung cancer
Nonasthmatic eosinophilic bronchitis
Chronic cough.
Most common causes. Other causes?
GERL
ACEI
Chronic cough. scheme.
1st step - suspected etiology on history and physical –> evaluate and treat as indicated. ACEI?
Stop ACEI
Chronic cough. scheme.
1st step - suspected etiology on history and physical –> evaluate and treat as indicated. UACS?
First generation H1 blockers
Chronic cough. scheme.
1st step - suspected etiology on history and physical –> evaluate and treat as indicated. Asthma?
PFTs (pulmonary function tests)
Chronic cough. scheme.
1st step - suspected etiology on history and physical –> evaluate and treat as indicated. GERD?
PPI
Chronic cough. scheme.
1st step - suspected etiology on history and physical –> evaluate and treat as indicated. ACEI, UACS, Asthma, GERD –> no improvement –>?
Chest X ray
Chronic cough. scheme.
1st step - suspected etiology on history and physical –> kitas langelis su simptomais (ne vaistu langelis) ? 3
Parenchymal disease
Purulent sputum/immunocompromised
No specific etiology
After this evaluation next step is chest xray
Chronic cough. asthma evaluation?
PFTs or 2-4 weeks of inhaled glucocorticoids (if the cough improves
–> diagnosis is made).
Chronic cough.
ACEI: due to impaired metabolism of kinins and substance P.
Increased production of prostaglandins by kinins. Increased thromboxane
levels as well.
.
Acute bronchitis.
Etiology?
Preceding respiratory illness (90 proc viral)
Acute bronchitis. clinical? 3
Cough
Absent systemic fundings (fever, chills)
Wheezing or rhonchi, chest wall tenderness
Acute bronchitis. clinical. cough characteristic?
> 5 days to 3 weeks
Can be productive (yellow, green, or purulent sputum)
Acute bronchitis.
Diagnosis?
Diagnosis is clinical
Acute bronchitis.
Diagnosis. when do xray?
only when suspected pneumonia
Acute bronchitis.
Symptomatic treatment?
Abs?
Nsaids/acetaminophen and or bronchodilators
abs ARE NOT recommended
Acute bronchitis. what viruses?
Influenza A or B, parainfluenza, adenovirus
Acute bronchitis. what may be sputum?
bloddy sputum
Upper airway cough syndrome. called ,,postnasal drip syndrome”
.
Upper airway cough syndrome. presentation?
It presents as chronic cough caused by:
a. Rhinosinus conditions: Allergic rhinitis, perennial nonallergic rhinitis, Vasomotor rhinitis
b. Acute nasopharyngitis
c. Sinusitis
Upper airway cough syndrome. what clinical may be reported?
Some patients report liquid dripping into the back of the throat or frequent throat clearing
episodes
Upper airway cough syndrome. treatment?
1st generation H1 blocker (eg, diphenhydramine)
OR
Combined antihistamine-decongestant (eg, brompheniramine and pseudoephedrine)
Upper airway cough syndrome. if do not respond to treatment after 2-3 weeks?
i. Further investigation (eg, sinus imaging, PFTs, high-resolution CT scan of chest)
ii. Empiric sequential therapy for GERD, cough-variant asthma, chronic sinusitis,
and non-asthmatic eosinophilic bronchitis
Acute bronchitis. symptomatic treatment?
nonprescription pain relievers
Acute bronchitis. treatment for cough?
Throat lozenges and OTC cough suppressants (eg, dextromethorphan/guaifenesin)
Acute bronchitis. treatment. bronchodilators?
Inhaled bronchodilators (eg, albuterol) are recommended in patients with wheezing in the setting of underlying pulmonary disease (eg, asthma)
Acute bronchitis. treatment. abs??
Antibiotics should NOT be given
Acute bronchitis. xray for what? 3
i. Suspicion of pneumonia
ii. Elderly patients (because signs of pneumonia may be subtle in these patients)
iii. Patients with advanced lung disease (eg, COPD)
Chronic bronchitis. definition?
3 consecutive months of productive cough in 2 successive years.
Chronic bronchitis. leading cause?
smoking
Chronic bronchitis. symptoms?
a. Chronic smoking (>=1 pack a day for at least 20 years)
b. Productive cough
c. Dyspnea on exertion
Chronic bronchitis. diagnosis, test?
PFTs
Chronic bronchitis. PFTs pattern? DLCO?
i. Obstructive pattern on spirometry
ii. Normal DLCO
Chronic bronchitis. Differentials?
iCompared to chronic bronchitis, bronchiectasis is associated with a history of recurrent respiratory tract infections and chronic cough with daily production of copious mucopurulent sputum.
Chronic bronchitis vs emphysema.
bronchitis DLCO?
normal
Chronic bronchitis vs emphysema.
emphysema DLCO?
decr. DLCO
Chronic bronchitis vs emphysema.
bronchitis xray?
prominent bronchovascular markings and a mildly flattened diaphragm
Chronic bronchitis vs emphysema.
emphysema xray?
decreased vascular markings and hyperinflated lung
Chronic bronchitis vs emphysema.
bronchitis hypoxemia?
more pronounced hypoxemia
Chronic bronchitis vs emphysema.
emphysema hypoxemia?
less pronounced hypoxemia