pulm meds and old stuff

Question 1

beta adrenergic

Answer 1

SABA - albuterol**
LABA

Question 2

muscarinic receptor stim

Answer 2

increased cGMP and enhanced bronchoconstriction (para)

Question 3

adrenergic B2 receptor stim

Answer 3

increased cAMP and bronchodilation (symp)

Question 4

B2 receptor agonist

Answer 4

inc bronchodlation

Question 5

Cholinergic antagonist/Anticholinergics drugs would counter

Answer 5

what PNS does increases airflow

Question 6

anticholinergic muscarinic antagonist
diseases

Answer 6

good for emphysema and bronchitis
NOT for asthma

Question 7

anticholinergic muscarinic antagonist drugs types

Answer 7

SAMAs
LAMAs

Question 8

glucocorticoids

Answer 8

Used to control inflammation-mediated bronchospasm
Reverses inflammation induced increase in vascular permeability
Prednisone

Question 9

Xanthine derivitives

Answer 9

Ex: caffeine
Causes bronchodilation
Mechanism: inhibition of phosphodiesterase (causes bronchoconstriction) → then in which will increase cAMP (bronchodilation) along w/ anti inflammatory

Question 10

antitussives

Answer 10

Used for dry coughs to suppress it
Ex: codeine

Question 11

decongestants

Answer 11

usually alpha 1 adrenergic agonists - cause vasoconstriction
Decreases permeability - want this
Can mimic effects of increased Sympathetic NS

Question 12

antihistamines

Answer 12

Histamine receptors:
H1 - located on:
vascular smooth muscles (vasodilation)
Vascular endothelial (increased vascular permeability)
CNS tissue throughout the body
sedation fatigue AEs

Question 13

2nd gen vs 1st gen antihistamines

Answer 13

2nd gen does not cross BBB

Question 14

leukotrines

Answer 14

pro inflammatory molecules that are important in mediating airway inflammation
- lukast
good for asthmatic

Question 15

mucolytics and expectorants

Answer 15

Mucolytics - decrease viscosity of mucus
Expectorants - facilitate expectoration of respiratory secretions by increasing the hydration of the airways
Stimulate bronchial secretions thus encouraging ejection of phlegm and sputum

Question 16

asthma

Answer 16

Chronic lung disease that inflames and narrows the airways
LABA - when pt needs to use rescue inhaler >2xweekly
20 mins before working out- educate pt about timing this w/ PT session
Last 12hrs
AEs: usually caused by improper administration
SABA - rescue inhaler
Avoid environments that worsen asthma

Question 17

restrictive lung

Answer 17

Difficulty fully expanding lungs with air - lungs are restricted or prevented from expanding

Question 18

polycythemia

Answer 18

inc RBC

Question 19

COPD

Answer 19

Umbrella term for: All these of obstruct their airway**
NOT a dx

Question 20

COPD umbrella

Answer 20

emphasema
chronic bronchitis
chronic asthma

Question 21

emphysema FCV/DVC

Answer 21

<0.5 very bad

Question 22

Restrictive vs obstructive

Answer 22

restrictive = inhalation disease
obstructive = exhalation disease

Question 23

forced expiration w/ emphysema

Answer 23

collapse during expiration

Question 24

hypoxic drive

Answer 24

emphysema pt start to rely on O2 to drive respiration instead of CO2
so supplemental O2 can confuse receptors

Question 25

Pink puffer emphysema

Answer 25

inc CO2
pursed lip
dyspnea
ineffective cough

Question 26

chronic bronchitits is characterized by

Answer 26

excessive mucus production

Question 27

Asthma why is it special

Answer 27

** know how this is different than other obstructive Diseases
episodic
upper respiratory obstruction

Question 28

Lung CA

Answer 28

small cell SCLC - located near hilum
non small cell NSCLC most common

Question 29

pulm hypertension

Answer 29

norm 15-18
5-10 above