Puberty Flashcards
Periods of reproductive system
1.Fetal period
2. Prepubertal period
3. Reproductive period
4. Senescence period
Fetal period
-Sex determination, differentiation, and tract development and growth
Prepubertal period
Period between birth and puberty
-includes secondary sexual growth and development. Second half of this period will have higher reproductive growth rate than rest of body growth
-varies in time depending on species
-somatic and behavioural secondary sex characteristics appear
Different stages of prepubertal period
-Early, mid, late-prepubertal and peri-pubertal stages
Reproductive period
Sexual activity resulting in conception and production of offspring is possible
Senescence period
Reproductive function is no longer possible
Patterns of secretion of GnRH and LH release
- Pulsatile (episodic or tonic)- short spikes
2.Surge (phasic or preovulatory)- sustained/long term
What factor plays a major role in differential sexual development of female vs male?
alpha fetoprotein (alpha-FP)
Female sex determination
1.alpha-FP binds to estradiol preventing it from passing the blood-brain barrier and entering the brain
2.Hypothalamus is therefore “feminized” resulting in GnRH surge center developing
Male sex determination
1.Testosterone freely enters the brain since alpha-FP does not bind to it
- Testosterone in the brain is aromatized into estradiol
- Hypothalamus is “defeminized” so surge center does not develop
Differences in LH secretion between males and females
Males: Small LH pulses every 2-6hrs. Testosterone immediately follows.
Females: High amplitude surges of LH every several weeks. Pulsatile releases of LH happen between surges
GnRH secretion before puberty
Before puberty, in both males and females, the GnRH neurons in both the tonic and surge centers release low amplitude and low frequency pulses of GnRH
GnRH secretion after puberty
-Males: do not have surge center
-Females: tonic center increases pulse frequency controling basal levels of GnRH.
Surge center controls preovulatory surge of GnRH
Maturation after puberty
Sexual maturation, physical maturation, and fertility potential all continue beyond onset of puberty
Definition of puberty in animals
Age at which reproduction and parentage first becomes possible