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Neuro > PTSD/OCD > Flashcards

PTSD/OCD Flashcards

1
Q

4 main Clusters of PTSD

A
  • Intrusion
  • Avoidance
  • Negative Alterations in Cognitions and Mood
  • Alterations in Arousal and Reactivity
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2
Q

Shown to improve all PTSD symptom clusters…

A

Sertaline (ZOLOFT)

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3
Q

Sertraline

A

ZOLOFT

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4
Q

Venlafaxine

A

EFFEXOR
Reduces avoidance/numbing and hyperarousal clusters

SNRI-Can increase BP

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5
Q

Nefazodone

A

SERZONE
Post synaptic 5 HT2
Improved symptoms in a vet population and showed equivalence to Sertraline in 2 fair trials
-Liver Toxicity prevents it from being 1st line, avoid in liver dx
LESS SEXUAL SIDE EFECTS THAN SSIRS

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6
Q

MAOI 2nd line for PTSD only one

A

Phenelzine

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7
Q

Phenelzine

A

NARDIL

Risk of HTN crisis, hypotension, anticholinergic effects

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8
Q

Monotherapy for PTSD Options….

A

Sertraline*
Paroxetine
Venlafaxine*
Fluoxetine

Nefazodone low

Imipramine veryylow
Phenelzine

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9
Q

Prazosin can be given for…

A

TX in association with nightmare (no recommendation f or or against)

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10
Q

Trauma Focused psychotherpies have what place in PTSD treatment

A

1st line

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11
Q

Acute phase of treatment

A

8-12 weeks

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12
Q

Preferred 1st Line for OCD

A

Fluoxetine
Sertraline
Fluvosamine
Paroxetine

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13
Q

Fluoxetine

A

Prozac

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14
Q

Fluvoxamine

A

Luvox

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15
Q

Paroxetine

A

Paxil

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16
Q

Sertraline

A

Zoloft

17
Q

TCA recommended as 2nd line for OCD Tx

A

Clomipramine

18
Q

Clomipramine

A

5HT, NE, Muscarinic, H1, Alpha1, Sodium channels in heart and brain

Major Active Metabolite

Major SE
Orthostatic hypotension, dizziness, arrhytmias, Anticholinergic, Histamine related sedation and weight gain

19
Q

Risks to consider with clomipramine…

A

Lethality in overdose in pts with suidical ideation

QT
Seizures
Anticholinergic (effect narrow angle glaucoma, contipation, elderly probs)

20
Q

Augmentation for refractory patients may consider adding..

A

Memantine or Topiramate

Also discussed that Abilify may help as well

21
Q

Clinical tool for OCD

A

YBOCS

22
Q

1st line for Kids OCD

A

CBT + SSRI

Neuro (12 decks)

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