Delirium Flashcards

1
Q

Delirium develops…

A

Over a short period of time–>hours to days

Fluctuates in severity during course of the day

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2
Q

Delirium Presents with what symptoms…

A
Anxiety
Change in sleep patterns
Irritability
Restlessness
Distubance in consciousness, cognition, and motor function
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3
Q

Ways to rank severity of Delirium…

A

Confusion Assessment Method (CAM)
MMSE
Delirium Rating Scale

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4
Q

Haloperidol

A

HALDOL
AGENT OF CHOICE FOR DELIRIUM
No IV
Avoid in pts with hepatic insufficiency or parkinsons
Associated with mortality in elderly with dementia
EPS, QT

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5
Q

Olanzapine

A

ZYPREXA
Associated with mortatlity in elderly with dementia
EPS, QT

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6
Q

Quetiapine

A

SEROQUEL

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7
Q

Risperidone

A

RISPERDAL

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8
Q

Lorazepam

A

ATIVAN

Can worsen the delirium

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9
Q

Trazodone

A

Give at bedtime, may cause over sedation
2nd line agent
Associated with prolonged and worsening delirium symptoms

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10
Q

Medications for Delirium Treatment….

A
Haloperidol (HALDOL)
Olanzapine (ZYPREXA)
Quetiapine (SEROQUEL)
Risperidone (RISPERDAL)
Lorazepam (ATIVAN)
Trazodone
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11
Q

Shown to decrease Suicidality in Bipolar…

A

Lithium

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12
Q

Shown to decrease Suicidality in Schizo…

A

Clozapine

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13
Q

For suicide, you should treat the underlying disorder….

A

Antidepressent-SSRI ans SNRIs preferred

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14
Q

Acute Pscyh patient with no known history….

A

Haloperidol + Lorazepam PO IM IV

-Add Benadryl or Benztropine to help decrease EPS

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15
Q

Acute Psych patient with known or suspected underlying psychotic illness…

A

Continue tx with current antipsychotic

-Initiate PO Olanzapine or Resperidone
WITH OR WITHOUT
Lorazepam

  • IM Olanzapine or Ziprasidone
  • Haloperidol + Lorazepam*
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16
Q

If Acute mania is suspected, load with…

A

Divalproex

17
Q

Oral Dissolving Tablets for treatment of Acute Agitations…

A

Olanzapine (ZYPREXA)
Risperidone (RISPERDAL MTABS)
Asenapine (SAPHRIS)
Aripiprazeol (ABILIFY, DISCMELT)

18
Q

Acute Agitation treatment strategy….

A

Attempt Non-Pharm
RX needed: give pt current med, or one that can be used in the future
Offer Oral meds 1st: Reg tab or ODT

Usually have to utilize Parenteral Antipsychotics and BZDs

19
Q

RAPID Tranq IM formulations…

A

Ziprasidone

Olanzapine

20
Q

Rapid Tranq rapid dissolve tabs formulations…

A

Olanzapine

Risperidone

21
Q

Rapid tranq IM Benzo…

A

Lorazepam

22
Q

Rapid tranq 1st gen antipsychotics….

A

Haloperidol available for injection and PO

23
Q

Haloperidol should be administered with….

A

Benadryl for EPS

24
Q

Important interaction with Olanzapine

A

DONT GIVE IM OLANZAPINE WITH IM LORAZAPAM DUE TO RISK OF RESPIRATORY DEPRESSION AND ORTHOSTATIC HYPOTENSION