PT APTT ( Coagulation Test)

Question 1

Prothrombin time ref range

Answer 1

11-13 seconds

Question 2

What is the PT used for

Answer 2

To assess the deficiencies of extrinsic and common pathway

Question 3

What is STYPVEN time for?

Answer 3

It is a variation of PT test that uses Russell’s viper venom instead of lipoprotein as an activator, bypassing the activation of Factor VII and directly activates factor X.
- It is used to differentiate between factor X and factor VII deficiency.

Question 4

INR (International Normalized Ratio)

Answer 4

Standardized reporting of the PT worldwide, because the result will not be dependent on the type of reagent or instrument use for determining the result.

Question 5

Panic value for INR

Answer 5

> 3.5

Question 6

Why is APTT being tested?

Answer 6

To assess the deficiencies of intrinsic and common pathway

Question 7

Reagents used in PT

Answer 7

• Tissue extract from brain and lung tissue
• Phospholipids
• CaCl2

Question 8

Reagents used in APTT

Answer 8

• Phospholipids
• Contact activator (silica, ellagic acid or kaolin)
• CaCl2

Question 9

Reference range for APTT

Answer 9

25 - 35 seconds