Psychotic Disorders Flashcards

You may prefer our related Brainscape-certified flashcards:
1
Q

Dopaminergic pathway associated with negative symptoms of schizophrenia

A

Mesocortical pathway

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Disorder associated with impairment of excitation-inhibitory balance due to altered NMDA signaling

A

Schizophrenia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Most common dopamine subtype targeted in schizophrenia

A

D2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Most commonly used substance among patients with schizophrenia

A

Nicotine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Smoking inc/dec levels of antipsychotic

A

Decrease, due to increasing metabolism

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

T/F. Being female is associated with a better prognosis for schizophrenia.

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Disorder where affected person thinks his genitals are regressing or retracting into his body, which will lead to subsequent death

A

Koro disorder

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Syndrome found amongst the Cambodian population where individuals perceive wind-like substances as causing distress, anxiety, palpitations, and other autonomic symptoms

A

Khyâl attacks or khyâl cap

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Prevalence rate of monozygotic twin of schizophrenia whose twin has this disorder?

A

47%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Prevalence of schizophrenia in general population?

A

1%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Low platelet monoamine oxidase levels are associated with the diagnosis of ____

A

schizophrenia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Peak age of onset of schizophrenia in women

A

25-35 years old

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

On head imaging patients with schizophrenia can be seen with increased/decreased ventricular size

A

Increased

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

ECT in pregnancy: Fetal heart rate must be checked before and after each session when gestational age is over ___ weeks.

A

10

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Patients with schizophrenia have increased/decreased volume of the hippocampus, parahippocampal gyrus, and amygdala on imaging

A

decreased

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Understimulation of NMDA receptors by glutamate is thought to cause this psychiatric symptom

A

Psychosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

More studies are being done with the association of negative symptoms for schizophrenia and this neurotransmitter

A

Glycine

18
Q

The hippocampus, amygdala, and parahippocampal gyrus are reduced/enlarged in size in patients with schizophrenia

A

REDUCED

19
Q

Schizoaffective disorder requires __ weeks of psychotic symptoms in the absence of mood symptoms

A

2

20
Q

Kraeplin’s 4 A’s

A

Associations, Affect, Autism, and ambivalence

21
Q

The dopamine hypothesis of schizophrenia indicates that higher amphetamine provoked dopamine release indicates better/worsening psychotic symptoms

A

worsening

22
Q

Pt brought to outpatient clinic for first eval of schizophrenia. When should they follow up after being prescribed antipsychotic?

A

1-3 weeks.

23
Q

Malaysian cultural syndrome that begins with sudden rampage (suicidal/homicidal) and ends in exhaustion and amnesia

A

Amok

24
Q

Delusional fear displayed by Native American Indians of being turned into a cannibal through possession by a supernatural monster

A

Wihtigo

25
Q

Cultural syndrome that occurs to female Eskimos of northern Greenland. It involves anxiety, depression, confusion, depersonalization, and derealization, ending in stuporous sleep and amnesia

A

Piblokto

26
Q

A sensation of an altered state in body organs without any special receptor apparatus to explain the sensation

A

Cenesthetic hallucination

27
Q

Late onset schizophrenia tends to occur after age ___, in this gender: _____

A

45, female

28
Q

fMRI has shown decreased blood flow to the ____ lobes in schizophrenia

A

Occipital

29
Q

T/F: One can see increased basal ganglia nuclei on an MRI for a patient with schizophrenia

A

True

30
Q

Recent meta-analyses found that first-generation immigrants have a ____ times increased risk of a brief psychotic disorder relative to the general public.

A

2

31
Q

Pt w/ Chrohn’s Dz with sx of Wernicke’s encephalopathy. Next step?

A

Start thiamine 200 mg TID parenterally

DO NOT obtain labs to confirm deficiency, must have prompt treatment

32
Q

Concordance rate of schizophrenia in dizygotic twins

A

14%

33
Q

Risk of schizophrenia in a child who has one parent with schizophrenia

A

10%

34
Q

Slowed thought processes; a condition seen in schizophrenia and in Parkinsonism

A

Bradyphrenia

35
Q

A family history of psychosis, younger age of onset of seizures, borderline intellectual function, and presence of complex partial seizures are correlated with the development of chronic interictal ___ in patients with epilepsy.

A

psychosis

36
Q

It is theorized that the α7 ____ _____ receptor (α7 nAChR) dysfunction is a primary driver of cognitive dysfunction in schizophrenia patients.

A

Nicotinic Acetylcholine

37
Q

Approximate annual relapse rate for patients with schizophrenia who are adherent in taking antipsychotics

A

30-40%

38
Q

This anatomical structure is associated with auditory hallucinations in patients with schizophrenia

A

Arcuate fasciculus

39
Q

Percentage of pts with schizophrenia who die by suicide

A

5-10%

40
Q

Percentage of pts with schizophrenia who attempt suicide

A

20%