Psychotic Conditions Flashcards
What are the types of mood disorders?
Depressive disorder
Bipolar disorder- sustained low and sustained high mood, affecting function of patient.
Persistent mood disorder.
What is depression?
Second largest cause of disability in the world.
2-3x more common in patients with chronic health problems
More common in divorced/separated, chronic alcoholism, redundancy, bereavement etc.
M:F 1:2
Wellbeing- biological, cognitive function, day to day working, planning etc affected at every level.
What are the core symptoms of depression?
Core symtpoms-
Continous low mood for at least 2wks
Lack of energy
Lack of enjoyment-interest anhedonia
Biological (somatic) symptoms-
Sleep changes 2/3rds insomnia, but younger pts hypersomnia (sleeping too much)- EMW (early morning wakeming- 2hrs before roughly)
Appetite and weight loss
Diurnal variation of mood- Morning worse, feel slightly better by evening.
Psychomotor retardation/agitation, dont want to move.
Loss of libido
Cognitive symptoms- negative view of self and project onto future i.e. im no good, no one likes me, my future is no good.
Low self esteem
Guilt/self blame- may focus on a small negative thing we did and multiply it by x100
Hopelessness
Hypochondrial thoughts
Poor concentration/attention so memory may be affected
Suicidal thoughts
What are some biological symptoms of depression?
Biological (somatic) symptoms-
Sleep changes 2/3rds insomnia, but younger pts hypersomnia (sleeping too much)- EMW (early morning awakening ≈ 2hrs before usual)
Appetite and weight loss
Diurnal variation of mood- Morning worse, feel slightly better by evening.
Psychomotor retardation/agitation, don’t want to move.
Loss of libido
Suicidal thoughts
What are some cognitive symptoms of depression?
Cognitive symptoms- negative view of self and project onto future i.e. I’m no good, no one likes me, my future is no good.
Low self esteem
Guilt/self blame- may focus on a small negative thing we did and multiply it by x100
Hopelessness
Hypochondrial thoughts
Poor concentration/attention so memory may be affected
Suicidal thoughts
How is depression diagnosed?
1) Mild- 2 core + 2 others (able to function)
2) Moderate- 2 core + 3/4 others
3) Severe 3 core + at least 4 others
4) Severe with psychotic symptoms
What are the differentials for depression?
Alcohol misuse Borderline personality disorder Dementia Delirium Schizophrenia
Cushing’s syndrome
Thyroid disease
HyperPTH
What is psychotic depression?
Hallucinations (auditory most common and negative)
Delusions (hypochondrial/guilt/nihilistic/persecutory i.e. world is coming to an end, patient says they’re dead
What is post natal deprssion?
10-15% of motherz within 1-2 months post partum
Worried about babys health and ability to care for baby
RF- FHx depression, older mother, single mother, poor social support, previous PND.
How is depression managed?
What are the symptoms of hypomania?
Mildy elevated, expansive or irritable mood. Increased energy/activity Positive view of oneself Increased self esteem Socialibility, talkative, over familiarity Increased sex drive Reduced need for sleep Difficulty of focusing on one task
Some pt enjoy the hypomania state.
What are the symptoms of mania?
Elevated/expansive/irritable mood (1wk)
Increeased energy/activity (inc agitation)
Grasniosity/increased self esteem
Pressure of speech- very apparent symptom
Flight of ideas/ racing thoughts
Distractible
Reduced need for sleep
Increased libido
Social inhibitions lost
Psychotic symptoms- believe they have super powers, think theyre a prophet etc.
Judgement impaired i.e getting loan to order two mercedes because different colours look nice.
What is a persistent mood disorder?
Cyclothymia-
mild periods if elation/ depression (needs ti be present for 2yrs).
Ealry onset/ chronic course
Common in relatives of BPD
Dysthymia-
Chronic low mood not fulfilling the criteria of deprssion
What is a mixed affective state?
Mixture or a rapid alternation (within few hrs) of hypomanic, manic and depressive symptoms.
How is bipolar classified?
1- 1 or > manic epsiodes or mixed episodes +/- 1 or > depressive episodes
2- 1 or > depressive episodes with at least 1 hypomanic episode
ICD 10- at least 2 epsiodes one of which must be hypomanic, manic or mixed episodes.
What is the epidemiology of bipolar?
1-2% prevalence
Onset 25yrs
M=F
Increased suicide rate
What are the differential diagnosis of mood disorders?
Normal fluctuations of mood PTSD Adjustment disroders i.e. bereavement Dementia Personality disorders Anxiety disorders
What are the causes of mood disorders?
Biological- genetics (depression x3 if first degree family relative), brain illnesses, physcial illness (chronic)
Psychological- childhood expereinces, view of yourself and fhe world, personality traits (i.e. obsessive persoanlity)
Social- housing, finance, work, relationships, support etc.
What are the treamtents of mood disorders?
Biological- pharmacological (antidepressants, mood stabilisers (lithium most effective), anti-psychotics, anxiolytics), ECT, rTMS (non invasive), tDCS
Psychological- Psychoeducation (about illness, relapse,medication), CBT, IPT, psychodynamic therapy, mildfullness.
Social- targeted interventions- family, housing, finance, employment, general coping strategies.
What is ECT?
2 times a wk for 12wks
Send electric current thriugh the brain to trigger an epileptic seizure.
Indications: severe depressive illness
Life threatening (food/fluid not), prolongued snd severe manic epsiode, caratonia, high suicide risk, stupor, severe psychomotor rtardation.
Whatbis the prognoiss of derpression?
First epsiode- Continue AD for 6-12 months. 50% chance of a second episode. This increases to 80% after a second epsiodes.
Multiple episodes- Continue AD for much longer
10% chance of severe unremitting depression
What is the prognosis of bipolar disorder?
Poor if:
Severe epiosdes, early onset, cognitive deficits.
Treatment is more effective ealier in the course of illness
80% relapse after first epsiode within 5-7yrs
But inbetween epsiodes will stabilise their moods.