Psychotherapeutic Drugs Flashcards
Risperidone IM injection duration
Approx. 2 weeks
MAOI’s tyramine foods
aged mature cheeses, smoked, pickled meats, yeast extracts, red wines, italian broad beans
Ingestion of tyramine foods with psychotherapeutics leads to:
hypertensive crisis, which may lead to cerebral hemorrhage, stroke, coma or death
Involuntary muscle symptoms similar to those of PD
extrapyramidal symptoms
Distressing muscle restlessness
Akathisia
Painful muscle spasms
acute dystonia
What medication is used to treat extrapyramidal symptoms?
benztropine (Cogenetin) and trihexyphenidyl (Artane)
Drug of choice for mania
Lithium
When levels of litihium exceed 1.5-2.0 mmol/
L begin to produce toxicity including GI discomfort, tremor, confusion, somnolence, seizures, and possibly death
Lithium toxicity
What helps maintain therapeutic lithium levels
Normal sodium range
What is the therapeutic level for lithium?
0.6-1.2 mmol/L
Clozapine (Clozaril) AE:
blood dyscrasia- any disorder affecting the blood, lymphoid tissue, bone marrow, or blood coagulation process
St. John’s wart interactions
tyramine foods, MAOIs and SSRIs
What is somnolense?
sleepiness during the day
Antidepressant onset
May take up to 8 weeks to see therapeutic effects
SSRI patient teaching:
Fiber supplement must be taken atleast 2 hrs before or after to avoid interaction with drug absorption.
Which drugs require a tapering dose of 2 months to discontinue
SSRIs
Discontinuation syndrome
happens with or without tapering. Dizziness, diarrhea, movement disorders, insomnia, irritability, visual disturbances, lethargy, anorexia, and lowered mood
A rare collection of symptoms resulting from elevated levels of neurotransmitter serotonin; may occur with use of any psychotropic drug that enhances brain serotonin activity such as antidepressants, buspirone, tramadol
serotonin syndrome
A potentially hazardous adverse effect of any drug or combination drug with serotonergic activity
serotonin syndrome