Cholinergic Drugs Flashcards
The nurse is reviewing the use of bethanechol (Duvoid) in a patient who is experiencing postoperative urinary retention. Which statement best describes the mechanism of action?
a) it causes decreased bladder tone and motility
b) it causes increased bladder tone and motility
c) it increases the sensation of a full bladder
d) it causes the sphincters in the bladder to become tighter
b) it causes increased bladder tone and motility
The family of a patient who was recently diagnoses with Alzheimer’s disease asks about the new drug prescribed to treat this disease. The patient’s wife says “I’m so excited that there are drugs that can cure this disease!” I cannot wait for him to start treatment. Which reply from the nurse is most appropriate?
a) the sooner he starts on the medicine, the sooner it can have it’s effect
b) these effects wont be seen for a few months
c) these drugs do not cure Alzheimer’s disease. Tell me what you understand about what starting this treatment would mean for your husband.
d) his response to this drug therapy will depend how far along he is in the disease process.
c) these drugs do not cure Alzheimer’s disease. Tell me what you understand about what starting this treatment would mean for your husband
The nurse is giving a dose of bethanechol (Urecholine) to a postoperative patient. The nurse is aware that contraindications to bethanechol include:
a) bladder atony
b) peptic ulcer
c) urinary retention
d) hypothyroidism
b) peptic ulcer
A patient took an accidental overdose of a cholinergic drug while at home. The patient comes to the emergency department with severe abdominal cramping and bloody diarrhea. The nurse anticipates which drug will be ordered to treat this patient?
a) atropine sulphate
b) physostigmine
c) bethanechol (Duvoid)
d) phentolamine (Rogitine)
a) atropine sulphate
The nurse is reviewing the orders for a newly admitted patient who is to start edrophonium chloride (Tensilon). The nurse understands this drug is ordered for which reason?
a) to reduce symptoms and delay the onset of Alzheimer’s
b) to treat the symptoms of MG
c) to aid in the diagnosis of MG
d) to reverse the effects of nondepolarizing NMBDs after surgery
c) to aid in the diagnosis of myasthenia gravis
When giving intravenous cholinergic drugs, the nurse must watch for symptoms of a cholinergic crisis, such as which of the following? select all.
a) peripheral tingling
b) hypotension
c) dry mouth
d) syncope
e) dyspnea
f) tinnitus
b, d, e
The nurse is teaching a patient about the possible adverse effects of donepezil (Aricept) for Alzheimer’s. Which of these are possible adverse effects? select all
a) constipation
b) GI upset
c) drowsiness
d) dizziness
e) blurred vision
b, c, d
Antidote for overdose of cholinergic
atropine
Cholinergic drugs that act by making more acetylcholine (ACh) available at the receptor site, which allows ACh to bind and stimulate the receptor
indirect acting cholinergic drugs
Cholinergic drugs that bind to cholinergic receptors and activate them
direct acting cholinergic drugs
Receptors located postsynaptically in the effector organs (smooth muscle, cardiac muscle, glands) supplied by the parasympathetic fibers.
Muscarinic
A description of the action of the PSNS
rest and digest
The neurotransmitter responsible for the transmission of nerve impulses to the effector cells in the PSNS.
Acetylcholine
The enzyme responsible for breaking down ACh
Cholinesterase
The healthcare prescriber has prescribed Donepezil for a patient. The nurse understands the desired effects of cholinergic drugs come from stimulation of which receptors?
a) cholinergic
b) Nicotonic
c) muscarinic
d) ganglionic
c) muscarinic
