Psychotherapeutic Flashcards
What are the Typical Antipsychotics
Antipsychotic/Neuroliptic
“-azine”
Prochlorperazine
Thioridazine
Chlorpromazine
Haloperidol
What are the Atypical Antipsychotics
Antipsychotic/Neuroleptic
Aripiprazole
“-apine”
Quetiapine
Olanzapine
Clozapine
“-idone”
Risperidone
Ziprasidone
Whats the difference in action between Typical and Atypical Drugs
(Antipsychotic/Neuroleptic)
Typical: block dopamine receptors
Atypical: block both dopamine and serotonin receptors
Both limit the stimuli coming to the brain
Pharmacokinetics of administration for Antipsychotic/Neuroleptic’s
for injection we give smaller doses compared to oral doses
IM dose is 4-5 times the active dose of orals
Antipsychotic/Neuroleptic
Indications
schizophrenia
hyperactivity
combative and agitated behavior
severe behavioral problems in children
Antipsychotic/Neuroleptic
Contra/Caution
allergy/hypersensitivity
CNS depression
blood dyscrasias
parkinsons (made worse)
prolonged QT interval
conditions worsened by anticholinergic effects due to suppressing dopamine
liver, renal, cardiac disease (metabolized/excretion)
Antipsychotic/Neuroleptic
Adverse effects
CNS: drowsiness/sedation, weak, tremor
- Extrapyramidal effects: pseudoparkinsonism, dystonia, akathisia, tardive dyskinesia, neuroleptic malignant syndrome
Antiandrogen effects: galactorrhea, gynecomastia
Anticholinergic: constipation, dry mouth, nasal congestion
Hypotension
Antipsychotic/Neuroleptic
Drug-Drug
beta blockers: increased betablocker effect
alcohol: increase CNS effects
anticholinergics: worsen effects
Antipsychotic/Neuroleptic
Assessment
severe CNS or respiratory depression heart disease risk for prolonged QT interval bone marrow suppression glaucoma/urinary retention vitals, EKG, CNS assessment renal/hepatic labs with CBC
Antipsychotic/Neuroleptic
Nursing diagnosis
impaired physical mobility r/t EPS
decreased CO r/t hypotension effects
risk for injury r/t CNS effects and sedation
impaired urinary elimination r/t anticholinergic effects
Antipsychotic/Neuroleptic
implementation
parenteral forms needs pt to stay laying down for 30mins to avoid orthostatic hypotension
monitor CBC for bone marrow depression
gradual stopping to avoid quick withdrawal
comfort for dyskinesia
sugarless candy and ice chips for GI effects
void before taking
provide vision exams
takes WEEKS to take effect
Drugs for Bipolar Disorder
Lithium Aripiprazole Lamotrigine Olanzapine Quetiapine Ziprasidone
Lithium
Action
unknown how it works on manic phase
alters sodium transport to influence reuptake of neurotransmitters
Lithium
Pharmacokinetics therapeutic range
0.6 - 1.2 mEq/L
can experience toxicity
Lithium
Contra/Caution
allergy pregnancy/Lact significant renal or cardiac disease dehydration/risk for dehydration hyponatremia