Psychotherapetic Drugs Flashcards

0
Q

agoraphobia

A

an anxiety disorder that involves an intense fear of being in unfamiliar situations or places that may be difficult to leave or in which help may not be available in the event of having an unexpected panic attack or panic-like symptoms

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1
Q

affective disorders

A

emotional disorders that are characterised by changes in mood

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2
Q

akathisia

A

a movement disorder in which there is an inability to sit still; motor restlessness; it can occur as an adverse affect of psychotropic medications

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3
Q

anxiety

A

the unpleasant state of mind in which real or imagined dangers are anticipated and/or exaggerated

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4
Q

biogenic amine hypothesis

A

a theory suggesting that depression and mania are caused by alterations in the concentrations of dopamine and norepinephrine, and serotonin and histamine in the brain

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5
Q

bipolar disorder

A

a major psychological disorder characterised by episodes of mania or hypomania, cycling with depression; formerly called manic-depressive illness

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6
Q

depression

A

an abnormal emotional state characterised by exaggerated feelings of sadness, melancholy, dejection, worthlessness, emptiness, and hopelessness that impact the patient’s life and may be out of proportion to reality; signs include withdrawal from social contact, loss of appetite, and insomnia

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7
Q

dopamine hypothesis

A

a theory suggesting that dopamine dysregulation in certain parts of the brain is one of the primary contributing factors to the development of psychotic disorders (psychoses)

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8
Q

dyskinesia

A

term for abnormal and distressing involuntary movements; inability to control movements

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9
Q

dysregulation hypothesis

A

a theory that views depression and affective disorders as caused not simply by decreased or increased catecholamine and serotonin activity but by failure of the brain to regulate the levels of these neurotransmitters

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10
Q

dystonia

A

a syndrome of abnormal muscle contraction that produces repetitive involuntary twisting movements and abnormal posturing of the neck, face, trunk, and extremities; often caused as an adverse reaction to psychotropic medications

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11
Q

extrapyramidal symptoms

A

the term for signs and symptoms that resemble pathologic changes to the pyramidal portions of the brain; such symptoms include various motion disorders similar to those seen in Parkinson’s disease, and are an adverse effect associated with use of various antipsychotic drugs

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12
Q

gamma-aminobutyric acid

A

an amino acid in the brain that fictions to inhibit nerve transmission in the central nervous system

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13
Q

hypomania

A

a less severe and less potentially hazardous form of mania

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14
Q

mania

A

an acute illness characterised by an expansive emotional state, including extreme excitement, elation, hyperactivity, agitation, talkativeness, flight of idea, reduced attention span, increased psychomotor activity, impulsivity, insomnia, anorexia, and sometimes violent, destructive, and self-destructive behaviour

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15
Q

metabolic syndrome

A

a cluster of conditions (increased glucose level, increased blood pressure, abnormal cholesterol levels, excess body fat around the waist) occurring together that increases the risk of heart disease, stroke, and diabetes

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16
Q

neuroleptic malignant syndrome

A

an uncommon but serious adverse effect associated with the use of antipsychotic drugs and characterised by symptoms such as fever, cardiovascular instability, and myoglobinemia (presence in the blood of muscle breakdown proteins)

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17
Q

neurotransmitters

A

endogenous chemicals in the body that serve to conduct nerve impulses between nerve cells (neurons)

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18
Q

permissive hypothesis

A

a theory postulating that reduced concentrations of serotonin (5-hydroxytryptamine) is the predisposing factor in individuals with affective disorders

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19
Q

psychosis

A

(plural: psychoses) a type of serious mental illness that can take several different forms and is associated with being out of touch with reality; that is, the individual is unable to distinguish imaginary from real circumstances and events

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20
Q

psychotherapeutics

A

the treatment of emotional and mental disorders

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21
Q

psychotropic

A

capable of affecting mental processes; usually said of a medication

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22
Q

serotonin syndrome

A

a rare collection of symptoms resulting from elevated levels of the neurotransmitter serotonin; may occur with the use of any psychotropic drug (e.g. antidepressants, buspirone, tramadol) that enhances brain serotonin activity

23
Q

stigma

A

widespread negative perceptions of and prejudice toward a specific group of people such as those with mental illness

24
Q

tardive dyskinesia

A

a serious drug adverse effect characterised by abnormal and distressing involuntary body movements and muscle tension that is associated with the use of antipsychotic medications

25
Q

anxiolytic drugs

A

benzodiazepines: alprazolam [Xanax], clorazepate [Tranxene T-Tab], chlordiazepoxide [Librium], clonazepam [Klonopin], diazepam [Valium], lorazepam [Ativan], oxazepam [Serex]
miscellaneous: buspirone [BuSpar], meprobamate [Miltown], hydroxyzine [Vistaril]

26
Q

adverse effects of anxiolytic drugs: benzodiazepines

A

amnesia, anorexia, sedation, lethargy, fatigue, confusion, drowsiness, dizziness, ataxia, headache, visual changes, hypotension, weight gain or loss, nausea, weakness

27
Q

adverse effects of anxiolytic drugs: miscellaneous (buspirone)

A

paradoxical anxiety, dizziness, blurred vision, headache, nausea

28
Q

mood stabilisers

A

lithium carbonate [Lithobid], lithium citrate [Generic], antiepileptics (valproic acid, lamotrigine, topiramate, oxcarbazepine) [Depakote, Depakene, Lamictal, Topamax, Trileptal]

29
Q

antidepressants (first generation): tricyclics

A

amitriptyline [Elavil], amoxapine [Generic], clomipramine [Anafranil], desipramine [Norpramin], doxepin [Sinequan], imipramine [Tofranil], nortriptyline [Pamelor], protriptyline [Vivactil], trimipramine [Surmontil]

30
Q

antidepressants (first generation): tetracyclics

A

maprotiline (first generation) [Generic], mirtazapine (second generation) [Remeron]

31
Q

antidepressants (first generation): MAOIs

A

isocarboxazid [Marplan], phenelzine [Nardil], tranylcypromine [Parnate]

32
Q

antidepressants (second generation): SSRIs

A

citalopram [Celexa], escitalopram [Lexapro], fluoxetine [Prozac], fluvoxamine [Generic], paroxetine [Paxil], sertraline [Zoloft]

33
Q

antidepressants (second generation): SNRIs

A

duloxetine [Cymbalta], venlafaxine [Effexor], desvenlafazine [Pristiq]

34
Q

antidepressants (second generation): miscellaneous

A

bupropion [Wellbutrin], nefazodone [Generic], trazodone [Generic, Oleptro], vilazodone [Viibrya]

35
Q

adverse effects of mood stabilisers: lithium salts

A

GO discomfort, tremor, confusion, sedation, seizures, cardiac dysrhythmia, drowsiness, slurred speech, slowed motor abilities, weight gain, ataxia, hypotension

36
Q

adverse effects of mood stabilisers: antiepileptic drugs

A

dizziness, drowsiness, GI upset, weight gain, hepatotoxicity, pancreatitis, unusual eye movements, visual changes, behavioural changes, ataxia

37
Q

adverse effects of antidepressants (first generation): tricyclics

A

anorexia, dry mouth, blurred vision, constipation, gymecomastia, sexual dysfunction, altered blood glucose level, urinary retention, agitation, anxiety, ataxia, cognitive impairment, sedation, headache, insomnia, skin rash, photosensitivity, weight changes, orthostatic hypotension, blood dyscrasias

38
Q

adverse effects of antidepressants (first generation): MAOIs

A

dizziness, dyskinesias, nausea, syncope, hypotension

39
Q

adverse effects of antidepressants (second generation): tetracyclics (mirtazapine, maprotiline)

A

drowsiness, abnormal dreams, dry mouth, constipation, increased appetite, asthenia (muscle weakness)

40
Q

adverse effects of antidepressants (second generation): SSRIs

A

anxiety, dizziness, drowsiness, headache, mild GI disturbance, sexual dysfunction, asthenia, tremor

41
Q

adverse effects of antidepressants (second generation): SNRIs

A

dizziness, drowsiness, headache, GI upset, anorexia, hepatotoxicity

42
Q

adverse effects of antidepressants (second generation): miscellaneous (trazodone, bupropion)

A

dizziness, headache, sedation, nausea, blurred vision, tachycardia

43
Q

common symptoms of serotonin syndrome

A

delirium, agitation, tachycardia, sweating, myoclonus (muscle spasms), hyperreflexia, shivering, coarse tremors, extensor plantar muscle (sole of foot) responses

44
Q

severe symptoms of serotonin syndrome

A

hyperthermia, seizures, rhabdomyolysis, renal failure, cardiac dysrhythmias, disseminated intravascular coagulation

45
Q

conventional antipsychotic drugs: phenothiazines

A

chlorpromazine [Thorazine], fluphenazine [generic], perphenazine [generic], prochlorperazine [Compazine], trifluoperazine [generic], thioridazine [generic]

46
Q

conventional antipsychotic drugs: thioxanthene

A

thiothixene [Navane]

47
Q

conventional antipsychotic drugs: phenylbutylpiperidines

A

haloperidol [Haldol], pimozide [Orap]

48
Q

conventional antipsychotic drugs: dihydroindolone

A

molindone [Moban]

49
Q

atypical antipsychotic drugs: dibenzodiazepines

A

clozapine [Clorazil], loxapine [Loxitane], olanzapine [Zyprexa], quetiapine [Seroquel], asenapine [Saphris]

50
Q

atypical antipsychotic drugs: benzisoxazoles

A

lurasidone [Latuda], paliperidone [Invega], risperidone [Risperdal], ziprasidone [Geodon], iloperidone [Fanapt]

51
Q

atypical antipsychotic drugs: quinolinone

A

aripiprazole [Abilify]

52
Q

adverse effects of conventional psychotropic drugs (e.g. haloperidol)

A

akathisia, extrapyramidal symptoms, hypertension, neuroleptic malignant syndrome, confusion, headache, mild GI disturbance, dry mouth, amenorrhea, gymecomastia, visual disturbances, hyperpyrexia, oedema, tardive dyskinesia, skin rash, photosensitivity, weight gain, urinary retention

53
Q

adverse effects of atypical psychotropic drugs (e.g. clozapine, risperidone)

A

tachycardia, akathisia, agitation, asthenia, ataxia, seizures, dyskinesia, dizziness, drowsiness, headache, insomnia, dry mouth, dyspepsia, anxiety, increased appetite, weight gain

54
Q

psychotherapeutic drugs

A

alprazolam, amitriptyline, bupropion, buspirone, clozapine, diazepam, duloxetine, fluoxetine, haloperidol, lithium, lorazepam, mirtazapine, risperidone, selegiline transdermal patch, trazodone