Psychosis Flashcards

1
Q

Three things needed to define psychosis

A

delusions, hallucinations, disorganized thinking/speech/behavior

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

symptoms of schizophrenia

A

mania, severe depression, substance induced, medical condition, drug induced

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

person believes “he or she is being tormented, followed, tricked, spied on, or ridiculed”, or that their food is being poisoned

A

delusions of persecution

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

individual’s experiencing innocuous events or merecoincidences[1]and believing they have strong personal significance

A

ideas of reference

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

False belief that another person, group of people, or external force controls one’s general thoughts, feelings, impulses, or behavior

A

delusions of control

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

ixed, false belief that one possesses superior qualities such as genius, fame, omnipotence, or wealth.

A

delusions of grandeur

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

person may, for example, believe that he or she has committed some horrible crime and should be punished severely. Another example is a person who is convinced that he or she is responsible for some disaster (such as fire, flood, or earthquake) with which there can be no possible connection.

A

delusions of guilt

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

psychotically depressed man believes his internal organs have become infested with and partially consumed by large purple worms.

A

somatic delusions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Three instances where you may see a patient having visual hallucinations

A

intoxication, withdrawal, delirium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

olfactory hallucinations are associated with an

A

epileptic aura

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what is the main cause of tactile perceptual disturbances

A

drug induced (cocaine or alcohol)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

hallucinating that you are being infested with bugs

A

Ekboms Syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

ideat that something is crawling around your skin

A

formication

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

MS, Alzheimers, Parkinson, tertiary syphilis, encephalitis, AIDS, neoplam, cerebrovascular, Huntingtons are all examples of

A

CNS causes of psychosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

hypo/hypercalcemia, hypopituitarism, hypo/hyperthyroidism, Addison, Cushing are all examples of

A

endocrinopathies that cause psychosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

B12, folate and niacin are examples of

A

nutritional/vitamin deficiencies that can cause psychosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What kind of hallucinations are seen in Lewy Body dementia?

A

happy hallucinations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

At what age do women and men present with schizophrenia?

A

women → 30

men → 20

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

If a patient over 55 presents with schizophrenia like symptoms what is the likely diagnosis?

A

dementia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Schizophrenia is also comorbid with

A

substance abuse

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

lower socioeconomic status secondary to impaired social functioning

A

downward drift

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Pathophysiology of schizophrenia is

A

increased dopamine activity in certain neuronal tracts → disease is most likely due to excess dopamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

what percent of schizophrenia patients smoke?

A

90%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

positive symptoms of schizophrenia

A

hallucinations, delusions, bizarre behavior, disorganized speech

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Negative symptoms of schizophrenia

A

blunted affect, anhedonia, apathy, alogia, avolition

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Psychotic disorders are ____ since they probably have origins in early development but are generally manifested in late adolescence as a result of the developmental trajectory of the brain

A

neurodevelopmental

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

1% of ____ is lost per psychotic episode

A

gray matter

28
Q

How will gray matter loss look on an MRI or CT?

A

gray matter atrophy and enlarged ventricles

29
Q

DSM V criteria for schitophrenia - you need ___ or more symptoms present for at least ____

A

2 or more

one month

30
Q

To be diagnosed with schizophrenia you need at least one of your symptoms to be

A

hallucinations, delusions, disorganized speech, grossly disorganized or catatonic behavior, negative symptoms

31
Q

For schizophrenia you have to have continuous disturbance for

A

6 months

32
Q

patients doesn’t talk, will give very simple answers to what they are asked

A

poverty of speech

33
Q

what types of associations may a schizophrenic patient have?

A

loose → tangential, circumstantial

34
Q

three phases of schizophrenia

A

prodromal → psychotics → residual

35
Q

what is going on in the prodromal stage?

A

accumulation of cognitive and functional impairment → start to see changes in mood, behavior, academic performance, self care, social withdrawal, sleep patterns, cognitions

36
Q

what percent of schizophrenic patients remain significantly depressed?

A

40-50%

37
Q

Symptoms of schizophrenia that indicate better prognosis

A

later onset, good social support, positive symptoms, mood symptoms, acute onset, female sex, few relapse, good premorbid function

38
Q

Symptoms of schizophrenia that indicate worse prognosis

A

early onset, poor social support, negative symptoms, family history, gradual onset, male sex, many relapses, poor premorbid function, cormorbid substance abuse

39
Q

which pharmacotherapy has better effect on the positive symptoms of schizophrenia?

A

FGA

40
Q

Common side effects of FGA

A

EPS, tardive dyskinesia, NMS

41
Q

MOA of FGA

A

dopamine antagonist

42
Q

MOST of SGA

A

5HT2 and D2 antagonists

43
Q

side effects of SGA

A

metabolic syndrome, EPS, hypotension, prolonged QTc, hyperprolactinemia

44
Q

best treatment for negative symptoms of schizophrenia

A

clozapine

45
Q

After giving patient antipsychotic they experience back spasms →

A

dystonia

46
Q

after giving patient antipsychotic they experience tremor, bradykinesia, and rigidity →

A

Parkinsonism

47
Q

After giving patient antipsychotic they experience darting and writhing movements →

A

tardive dyskinesia

48
Q

After giving patient antipsychotic they experience AMS, muscle rigidity, autonomic dysregulation (fever, hypertension, tachycardia) →

A

NMS

49
Q

“lack of insight” is a symptom of severe mental illness where the person is unable to understand and perceive their illness

A

anosognosia

50
Q

why do patients with schizophrenia or bipolar disorder refuse meds and therapy?

A

anosognosia

51
Q

What percent of schizophrenia and BPAD patients experience anosognosia?

A

schizophrenia → 50%

BPAD → 40%

52
Q

Duration to be considered a Brief Psychotic Disorder

A

< 30 days

53
Q

Symptoms of Brief Psychotic Disorder

A

delusions, hallucinations, disorganized speech (derailment or incoherence), grossly disorganized/catatonic behavior

54
Q

Onset of Brief Psychotic Disorder is most likely due to

A

acute stress

55
Q

Prognosis of Brief Psychotic Disorder

A

return to premorbid baseline

56
Q

Duration for schizophreniform disorder

A

1-6 months

57
Q

duration for schizophrenia

A

> 6 months

58
Q

Schizophrenia + Manic Depression

A

schizoaffective disorder

59
Q

Patients with schizoaffective disorder meet the criteria for

A

major depressive episode, manic episode, or mixed episode when also meeting the criteria for schizophrenia

60
Q

Schizoaffective disorder a patient must have ____ for 2 weeks in the absence of mood symptoms

A

positive symptoms

61
Q

In schizoaffective disorder what must be present for a substantial portion of the psychotic illness

A

mood symptoms

62
Q

belief that a person is in love with the affected individual, despite contrary evidence

A

erotomanic delusion

63
Q

fantastical beliefs that one is famous,omnipotent, wealthy, or otherwise very powerful. The delusions are generally fantastic and typically have areligious,science fictional, orsupernaturaltheme

A

grandoise delusion

64
Q

fixed, false belief that one’s bodily functioning, sensation, or appearance is grossly abnorma

A

somatic delusion

65
Q

A person with this type of delusional disorder believes that his or her spouse or sexual partner is unfaithful.

A

jealous delusion

66
Q

People with this type of delusional disorder have two or more of the types of delusions listed above.

A

mixed type delusion