Psychosis

Question 0

Causes of psychosis

Answer 0

Functional - schizophrenia, bipolar
Medical - epilepsy, Alzheimer’s, dementia, HIV, neurosyphilis
Drugs - cannabis, mantras, cocaine, amphetamines
Prescription - steroids, antiparkinsons, atropine
Post partum

Question 1

Define psychosis

Answer 1

Loss of contact with reality

Question 2

Indications for neuroleptics

Answer 2

Primary - schizophrenia, mania, organic psychosis

Others - nausea, vomiting, hiccups, Tourette’s, anaesthesia

Question 3

Classes of neuroleptics

Answer 3

Classical/typical - dopamine 2 receptor antagonists

Atypical - D2, D3, serotonin receptor antagonists

Question 4

Egs of EPSEs

Answer 4

Acute dystonic reactions (young males) give anticholinergic

Parkinsonian signs (bradykinesia, rigidity, tremor)

Akathisia - motor restlessness

Question 5

Complications of neuroleptic a

Answer 5

Tardive dyskinesia (involuntary movements)

Neuroleptic malignant syndrome - increased temp, dehydration, febrile illness, catatonia (Rx dantrolene, bromocryptine [dopamine antagonist], benzodiazepine)

Question 6

What groups of patients are at risk with neuroleptics

Answer 6

Pregnant / lactating
Children (EPSE)
Elderly
Hepatic disease

Question 7

What to give for resistant psychosis

Answer 7

Clozapine

Question 8

Name typical neuroleptic a

Answer 8

Haloperidol

Phenothiazines - chlorpromazine