Psychosis Flashcards

1
Q

Define Psychosis

A

A mental state in which reality is greatly distorted

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2
Q

Name the three prevalent features of Psychosis and define them

A
  • *Delusions** (Fixed false belief held firmly despite evidence to the contrary)
  • *Hallucinations** (Perception in the absence of external stimuli)
  • *Thought Disorder** (impairment in the ability to form thoughts from logically connected ideas)
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3
Q

Describe the ICD10 class 1-8 of Psychotic Disorders

A

1 - Schizophrenia
2 - Schizotypal Disorder
3 - Persistent Delusional Disorder
4 - Acute and Transient Psychotic Disorder (<1m)
5 - Induced Delusional Disorder
6 - Schizoaffective Disorder
7 - Other non organic Psychotic
8 - Unspecified

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4
Q

most common psychotic disorder

A

schizophrenia

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5
Q

name some causes of psychosis

A

non-organic and organic

non-organic - schizophrenia, schizotypal disorder, schizoaffective disorder, acute psychotic episode

organic - iatrogenic, complex partial epilepsy, delirium, dementia, huntington’s, SLE

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6
Q

What is Schizotypal Disorder (AKA Latent Schizophrenia)?

A

Eccentric Behaviour, Suspiciousness, Unusual Speech and deviations of thinking and affect that is similar to those suffering from schizophrenia

No Hallucinations or Delusions

More common in those with a first degree relative with Schizophrenia

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7
Q

what is Mood disorders with psychosis?

A

psychosis develops secondary to depression or mania

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8
Q

What is Schizoaffective Disorder?

A

Symptoms of both Schizophrenia and Mood Disorder in the same episode, with mood disorder meeting criteria (mood disorder can be depression or mania)

mood symptoms should meet criteria for either a depressive illness or manic episode + 1 or 2 typical symptoms of schizophrenia

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9
Q

What is Persistent Delusional Disorder?

A
  • Single or set of delusions (often persecutory, grandiose, hypochondriacal) for at least 3 months in which delusions is the only or most prominent symptom
  • Other areas of thinking intact, unlike Schizophrenia
  • often responds well to antipsychotics
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10
Q

What is Folie à Deux?

A

‘Thought shared by two’

A delusional belief shared between two people.

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11
Q

Name three common types of Delusions

A

Grandiose
Persecutory
Hyperchondriacal

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12
Q

Name three ways of classifying Delusions

A

Cause: Primary vs Secondary
Mood : Congruent vs Incongruent
Plausibility: Bizarre vs Non Bizarre

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13
Q

Name four Organic Causes of Psychosis

A

Drug Induced
Iatrogenic (Steroids)
Dementia
Delirium

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14
Q

Define Schizophrenia

A

Most common form of Psychosis characterised by Hallucinations, Delusions and Thought Disorders which lead to functional impairment.

occurs in absence of organic disease, alcohol or drug-related disorders and is not secondary to elevation or depression of mood

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15
Q

Give three PREDISPOSING risk factors for Schizophrenia

A

bio = genetic, neurochemical, neurodevelopmental, age 15-35,

psychological = FHx, childhood abuse

social = substance misuse, low socioeconomic status, migrants, urban area, birth in late winter/early spring season

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16
Q

Give two PRECIPITATING risk factors for Schizophrenia

A

bio = Smoking Cannabis or psychostimulants

psych = Adverse Life Events, poor coping style

social = adverse life events

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17
Q

Give three PERPETUATING risk factors for Schizophrenia

A

bio = Substance Misuse, Poor Medication Compliance

psychological = adverse life events

social = Lack of Social Support

18
Q

What are Schneider’s First Rank Symptoms for Schizophrenia?

A

symptoms which, if 1 or more are present, are strongly suggestive of schizophrenia as alternative to ICD-10

  • Delusional Perception
  • Third Person Auditory Hallucinations
  • Thought Interference (Insertion, Withdrawal, Broadcast)
  • Passivity Phenomenon (They have no control)
19
Q

Positive symptoms are normally seen in the ‘Acute Phases’ of Schizophrenia, and can be remembered by ‘Delusions Held Firmly Think Psychosis’. What does this mnemonic stand for?

A
  • *D**elusions
  • *H**allucinations
  • *F**ormal Thought Disorder
  • *T**hought Interference
  • *P**assivity Phenomenon
20
Q

The negative symptoms are normally seen in the Chronic Phases of Schizophrenia. What are they?

A
  • Avolition - reduced motivation
  • Asocial behaviour - loss of drive for any social engagements
  • Anhedonia - lack of pleasure in activities that were previously enjoyable
  • Affect Blunted - diminished or absent capacity to express feelings
  • Alogia - Poverty of Speech
  • Attention deficits - may experience problems with attention, language, memory, executive function
21
Q

There are 7 main subtypes of Schizophrenia. Define Paranoid Schizophrenia.

A

Most common, dominated by positive symptoms

22
Q

There are 7 main subtypes of Schizophrenia. Define Post Schizophrenic Depression.

A

Depression predominates with Schizophrenic illness in the past 12 months, and some symptoms still present

23
Q

There are 7 main subtypes of Schizophrenia. Define Hebephrenic Schizophrenia.

A

Though disorganisation predominates
Illness onset is earlier (15-25)
Poorer Prognosis

24
Q

There are 7 main subtypes of Schizophrenia. Define Catatonic Schizophrenia.

A

Rare form characterised by one or more Catatonic Sx

25
There are 7 main subtypes of Schizophrenia. Define Simple Schizophrenia.
Rare form with negative symptoms only (no psychotic)
26
There are 7 main subtypes of Schizophrenia. Define Undifferentiated Schizophrenia.
Meets criteria for Schizophrenia but doesn’t fit in any categories
27
There are 7 main subtypes of Schizophrenia. Define Residual Schizophrenia.
One year of chronic negative symptoms preceded by a clear cut psychotic episode
28
What are the four symptoms in ICD10 Group A Criteria of Schizophrenia?
Thought Interference Delusions of Control/Influence/Passivity Running Commentary Auditory Hallucinations Bizarre Persistent Delusions
29
What are the four symptoms in ICD10 Group B Criteria of Schizophrenia?
Hallucinations in other modalities that are persistent Thought Disorganisation Catatonic Symptoms Negative Symptoms
30
What is required to diagnose Schizophrenia from ICD10 categories?
One clear symptom from Group A, and at least two from Group B For at least one month
31
Describe the expected Appearance, Behaviour, Speech and Thought of a Schizophrenic patient (MSE)
Appearance - may be normal or may have self neglect Behaviour - Positive (Preoccupied, Restless) or Negative (Withdrawn, Poor Eye Contact) Speech - Loosening of Associations, Thought Blocking Thought - Delusions, Thought Interference, Formal Thought Disorder (Circumstantiality)
32
Describe the expected Mood, Perception, Cognition and Insight of a Schizophrenic patient (MSE)
Mood - Incongruent Perception - Hallucinations Cognition - Orientated but attention and concentration impaired Insight - Poor
33
what bloods you would like to do for a Schizophrenic Patient
* FBC - anaemia and infection * TFTs - thyroid dysfunction can present with psychosis * Glucose/HbA1c (Antipsychotics can cause metabolic syndrome) * Serum Calcium (Hypercalcemia) * Baseline U&Es & LFTs for before giving antipsychotics * Cholesterol - atypical antipsychotics cause metabolic sydnrome * vit b12 and folate - deficiencies cause psychosis
34
Other than blood tests, name four investigations for Schizophrenia
* Urine drug tests * ECG (Antipsychotics can cause Long QT) * CT (rule out SOL) * EEG (Rule out Tempora Lobe Epilepsy)
35
Describe the pharmacological management of Schizophrenia
1) Atypical Antipsychotics (Risperidone, Olanzapine) 2) Clozapine reserved for treatment resistant Schizophrenia Adjuvants: Short term Benzodiazepines, Antidepressants, Lithium
36
When would you consider ECT for a Schizophrenic patient?
If Resistant or Catatonic
37
Name four potential psychological interventions for Schizophrenia
CBT Family Intervention Art Therapy Social Training Skills
38
How does Family Intervention help Schizophrenic patients?
Psychoeducation helps families decrease high levels of expressed emotion which reduces relapse rates
39
Name three Social Interventions that can be done for Schizophrenic Patients
* Support groups (Rethink, Sane) * Peer Support * Supported Employment Programmes
40
treatment of first-episode schizophrenia flow chart
41
Define Paraphrenia
Late onset schizophrenia characterised by positive symptoms Similar to Paranoid Schizophrenia but less severe Thought disorder and catatonic symptoms are rare