Psychopharmacology Flashcards
The tiny space between the terminal button and the dendrite of another neuron is called the _____.
Synaptic cleft
When a neural impulse reaches the end of an axon, it causes the tiny sacs at the end of the axon to release chemicals called ______.
Neurotransmitters
Most terminal buttons contain a number of tiny storage sacs called _____.
Synaptic Vesicles
The entire area composed of the terminal button, the synaptic cleft, and the dendrite or soma of the next neuron is called the _____.
Synapse
What is the purpose of endorphins?
It involved in the reduction of pain and enhancement of pleasure
A neurotransmitter that is associated with both schizophrenia and PD is _____.
Dopamine
What does an agonist do?
It mimics the effects of a natural neurotransmitter and do so by binding directly to a receptor site.
Acetylcholine is a neurotransmitter that is associated with the _____.
a. regulation of sleep
b. regulation of pain and pleasure
c. inactivation if synaptic processes
d. regulation of both memory and movement
e. modulation of anxiety
(d)
What is a postsynaptic potential (PSP)?
A PSP is dependent on the release of a neurotransmitter into the synaptic cleft that binds to a receptor site. A PSP is a graded response that affects the probability of a neuronal impulse based on its size and polarity
How many stages are involved in the transmission of a neuronal impulse across the synaptic junction.
Five
The site of neurotransmitter synthesis is _____.
Neuronal Soma. Neurotransmitter synthesis occurs within the soma, where the nucleus of a nueron is found
What happens with the release of neurotransmitters?
Following the release of neurotransmitters into the synaptic cleft, they may bind to receptor sites and if sufficient may trigger an action potential at the postsynaptic membrane. Neurotransmitters may then be inactivated by enzymes present in the synaptic cleft.
Receptor sites are located on _____
Postsynaptic membrane.
This membrane receives information from another neuron and contains receptor sites for this purpose.
Following the initiation of an action potential on the postsynaptic membrane, what might happen to the neurotransmitter?
Neurotransmitters may be taken up by the presynaptic membrane after a synaptic transmission for reuse.
Following reuptake of neurotransmitters, _____.
a. some will be stored in the receptor sites
b. some will be stored in the soma
c. some will be “resynthesized” in the vesicles
d. some will be stored in the synaptic vesicles
e. none of the alternatives is correct
(d)
