Psychopharmacology

Question 1

Dangers of TCAs?

Answer 1

Can overdose.

Question 2

How long for maintenance treatment for depression if:

1st episode
2 episodes within 5 years
3 or more within 5 years
Psychotic depression/suicide

Answer 2

6-12 month
3 years
5 years
Indefinite

Question 3

Common SSRI side effects:

Answer 3

GIT, N/V/Diarrhoea
Can increase anxiety
Sexual dysfunction.

Question 4

What side effect for SSRIs should you specifically ask for?

Answer 4

Sexual dysfunction

Question 5

How long to wait to trial for change of symptoms?

Answer 5

4-5 weeks

Try a different group

Question 6

How to monitor for clozapine SFx?

Answer 6

18 weeks of FBEs

1 year: Echo, ECG

Question 7

Criteria to start clozapine?

Answer 7

Need to trial at least 2 different antipsychotics before considering.

Question 8

What are eg. Of depots antipsychotics?

Answer 8

2nd
Aripiprizole
Olanzipine
Risperidone
Flupenthoxol

1st
Haliperidone
Zuclopenthixol

Question 9

Off label use of antipsychotics?

Answer 9

quetiapine

Anxiety

Question 10

Acute treatment of Mania?

Answer 10

Antipsychotics: olanzipine, Quetiapine, aripriprazole
Mood stabilizers: lithium, valproate, carbamazepine, lamotrigine

Consider ECT

Question 11

Which mood stabilizer is best for preg?

Answer 11

Lithium

Others like valproate and carbamazepine have worst sfx

Question 12

Are SSRIs addictive?

Answer 12

Nope

Question 13

Are benzos addictive?

Answer 13

Yes

Question 14

DDx of panic attacks?

Answer 14

MI, thyroiditis, pheo.

Question 15

Drug of choice anfor generalized anxiety disorder?

Answer 15

Venlafaxine

Question 16

Higher dose needed for anxiety or depression?

Answer 16

Anxiety

Question 17

NMS can use what blood test to distinguish from SS?

Answer 17

CpK levels are really high in NMS