Psychopharm intro Flashcards
1
Q
psych drugs need to be…
A
lipophilic- cross the BBB
2
Q
NE is synthesized where
A
locus coeruleus
3
Q
most serotonin and receptors are found where
A
gut- SSRIs can cause nausea/ stomach upset
4
Q
blood role of serotonin
A
plays a role in fn of platelets, 5HT induces platelet aggregation
SSRIs can cause bleeding (reuptake of 5HT in platelet is inhibited)
5
Q
list some manifestations of serotonin syndrome
A
clonus
tremor, hypertonia
inducible ocular clonus w/ agiation or diaphoresis
6
Q
key NE receptor in brain
A
alpha 1 and 2
7
Q
major inhibitory neurotransmitter
A
GABA- sleep and reducing memories