Psychopathology: OCD Flashcards

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1
Q

What are the behavioural characteristics of OCD?

A
  • compulsions - repetitive behaviours to reduce anxiety, 10% of patients with OCD only have compulsions
  • Avoidance - reduce anxiety by keeping away from triggers (e.g. could be avoiding regular situations and self-isolating)
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2
Q

What are the emotional characteristics of OCD?

A
  • anxiety and distress - unpleasant emotional experiences as anxiety accompanies obsession, can be very overwhelming
  • Accompanying depression - anxiety means low mood and lack of employment, leading to isolation and depression, compulsions bring temporary relief, but not permanent
  • Guilt and disgust - irrational guilt over a minor issue or for things out of your control which is directed towards oneself or something external, bringing negative emotions
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3
Q

What are the cognitive characteristics of OCD?

A
  • obsessive thoughts - 90% of OCD patients suffer with this. Recurring intrusive thoughts that makes compulsive behaviours to stop the thoughts - vary from person to person but always unpleasant
  • Cognitive dealing strategies - adopt coping strategies to manage anxiety with distractions from everyday life, which are disruptive
  • Excessive anxiety - Awareness that thoughts and behaviour are irrational, but they cannot get rid of them. They experience catastrophic thoughts and are hyper-vigilant of their obsessions - increasing anxiety.
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4
Q

What’s the genetic biological approach into explaining OCD - Candiate genes?

A

Researchers have identified specific genes which create a vulnerability for OCD, called Candidate genes.
- Serotonin Genes are implicated in the transmission of serotonin across synapses
- Dopamine Genes are implicated in OCD also. Both Dopamine and Serotonin are neurotransmitters that have a role in regulating mood.

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5
Q

What’s the genetic approach to explaining OCD - Polygenic genes and types of OCD?

A

OCD is not caused by one single genes but several genes are involved. This means it is polygenic.
- Evidence has been found that there are up to 230 genes involved in OCD.
—> One group of genes may cause OCD in one person but another group of genes may cause the disorder in another person. There is evidence that suggests different types of OCD may be the result of particular genetic variations, such as hoarding disorder.

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6
Q

What’s some support for genetic explanations of OCD?

A
  • there is some evidence that certain people are more vulnerable than others.
    —> Newstadt reviewed cases and found 68% of MZ twins both have OCD and 31% of DZ twins. This shows the role of genes as MZ twins have 100% same genes, whereas DZ have 50%. So high congruence in MZ twins show OCD is caused by genetic make-up rather than the environment.
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7
Q

What are some weaknesses to genetic explainations for OCD?

A

Too many candidate genes - psychologists are less successful pinning down the exact genes involved in the development of OCD. Each genetic variation found increases the possibility of OCD and therefore there are too many genes to create a specific explanation for OCD development - means its difficult to tackle so the genetic explanation has little practical applications to help cure and cope with the illness.
- environmental factors may be influential

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8
Q

What is the neural biological approach into explaining OCD - serotonin and dopamine?

A
  • The role of neurochemicals such as serotonin and dopamine - levels associated with abnormal transmission of mood-related info/ obsessive thoughts.
    —> serotonin: regulates mood, relays info from one neuron to another. Low serotonin means normal transmission of mood doesn’t happen - less serotonin in the brain means mood is effected and therefore obsessive thoughts develop
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9
Q

What do PET scans show about serotonin in the brain?

A

PET scans show low levels of serotonin activity in the brains of OCD patients and drugs that increase serotonin activity reduced the symptoms of OCD.

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10
Q

What have neuroimaging techniques enabled?

A

researchers to study the brain in detail to identify normal brain patterns -this therefore allows for comparisons with abnormal patterns.

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11
Q

What is the basal ganglia responsible for?

A

responsible for innate psychomotor functions. Rapaport and Wise proposed the hypersensitivity of the basal ganglia gives a rise to the repetitive motor behaviours seen in OCD (e.g. repetitive washing/cleaning/checking)

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12
Q

Why is the Orbitis Frontal Cortex (OFC) and Thalamus involved in OCD?

A

the OFC is the ‘worry circuit’ - the caudate nucleus-thalamus loop - inability to filter small worries in OCD so worry circuit is overactive- its also involved in decision making. This would result in increased anxiety and increased planning to avoid anxiety.
An overactive thalamus would result in an increased motivation to clean or check for safety. If the thalamus was overactive the OFC would become overactive as a result.

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13
Q

what do PET scans also show about the Orbital frontal cortex?

A

PET scans also show high levels of activity in the orbital frontal cortex which is associated with higher thought processes and sensory info. This is affected by impulses, therefore in OCD they have difficulty switching off the impulses, so they turn into obsessions, resulting in compulsive behaviour.

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14
Q

How does Zohar support neural explanations?

A

He gave mCPP (a drug that reduces serotonin levels) to 12 OCD patients and 21 non-OCD patients. Found that the symptoms of OCD patients were significantly enhanced (made worse). This supports the idea that sufferers condition was related to abnormal levels of serotonin.

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15
Q

What’s more support for levels of serotonin affecting OCD?

A

Hu (2006) compared serotonin activity in 169 OCD patients and compared 253 non-OCD patients. Found that serotonin levels were lower in the OCD patients, which supports the idea that low levels of serotonin are associated with OCD.

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16
Q

What’s some strengths of the neural explanation?

A
  • Allows for medication to be developed which helps sufferers (yet drugs are not completely effective)
  • Advances in technology have allowed researchers to investigate specific areas of the brain more accurately
  • supported by evidence - increasing the levels of serotonin reducing OCD shows that serotonin is involved in developing OCD.
17
Q

What are some weaknesses for neural explanations?

A
  • inconsistencies found in the research, as no system has been found that always plays a role in OCD
  • Cause and effect issue - the extent to which abnormal levels of serotonin cause OCD is limited by the fact it could be an effect of OCD, we cannot tell which came first.
  • Not all sufferers of OCD respond positively to serotonin enhancing drugs, which lessens the supports for the abnormal levels of neurotransmitters as it should work in all if it is totally related to serotonin.
  • It is generally thought that disorders that reduce immune functioning do not cause OCD, but may trigger symptoms in those more genetically vulnerable.
18
Q

What is Drug therapy for OCD?

A
  • using drugs to increase or decrease neurotransmitter levels
  • helps balance a chemical imbalance and therefore reduces the effects of OCD
19
Q

What are SSRIs (Selective Serotonin Reuptake Inhibitors)?

A
  • anti-depressants have been proven to work by increasing serotonin levels
  • neurotransmitters are released by neurons and pass through the pre-synaptic neuron through the synapse.
  • Neurotransmitters convey a signal from the pre-synaptic neuron to the post synaptic neuron and is then broken down and released.
  • drugs increased the synapse function so more neurotransmitters pass through and therefore function is increased and OCD symptoms reduced
  • the average dose is 20mg but usually changed after 3 months if successful
20
Q

What are some alternative drugs?

A

SNRI drugs - increases serotonin along with other neurotransmitters when SSRIs dont work
Tricyclics - same effects of SSRI drugs but have more extreme side effects so are less wanted unless absolutely necessary
Antipsychotic drugs reduce Dopamine (usually for Sz) have proved useful in OCD, but given if SSRIs don’t work.

21
Q

What’s some evidence to support drug treatments?

A

Julien (2007) reported that studies of SSRIs show that although symptom do not fully disappear between 50-80% of the patients with OCD improve, allowing them to live a normal lifestyle. This supports the use of drugs to treat OCD.

22
Q

What are some of the strengths to drug treatments?

A
  • effective - Soomro looked at 17 studies and they all found that SSRI are more effective than the placebo. For the remaining 30% when SSRIs didn’t work, alternatives are useful to an extent.
  • drugs are cheap to administer
23
Q

What are some of the weaknesses of drug treatments?

A
  • unreliable evidence - drug companies are biased towards positive results as they want to sell more drugs (false advertising, etc.) so cannot be certain whether drugs are as useful as is said.
  • Drugs are not a cure, they simple reduce the symptoms of the illness
  • Limitation is that there are side effects of these drugs, which can include sleep disruption, headaches, loss of appetite, drowsiness, etc. means quality of life does not totally improve and could deter people
  • Antidepressants are only suitable for adults and not young people
  • The drug can cause heightened level of suicidal thinking and become addictive
  • it needs to be combined with psychological treatment for long term reduction of symptoms.
24
Q

What did Bellodi et al find to genetics play a role in explaining OCD?

A

claim that genetic factors play a role in the disorder. Using evidence form twin and family studies, they showed that close relatives are more likely to have the disorder than more distant relatives.

25
Q

What did Pauls et al find to support genetic explanations of OCD?

A

there is much higher % of OCD sufferers in relatives of patients with OCD than in the control group without OCD.