Psychopathology Flashcards
2 studies that support the genetic explanation for OCD
- Nestadt: reviewed twin studies, found 68% concordance rate in MZ twins and 31% for DZ twins
- Lewis reported that of his OCD patients, 37% had parents with OCD and 21% had siblings
2 studies that support the neural explanation for OCD
- Gilbert found that OCD patients had bigger thalami than a control sample
- Galloway and Duffy found brain scans of OCD patients are structured and function differently to people without OCD
3 AO1 points on the genetic explanation for OCD
- polygenetic, multiple genes that can cause OCD
- SERT gene: implicated in the efficiency of transport of serotonin across synapses (lower levels of serotonin cause OCD)
- COMT gene: higher levels of dopamine
- Diathesis stress model proposes that certain genes leave individuals more likely to develop a disorder but that an environmental stress/trigger is needed to trigger the condition
3 AO1 points on the neural explanation of OCD
- high levels of dopamine are linked to compulsive behaviours
- low levels of serotonin found in OCD patients
- basal ganglia: dysfunction can affect communication in these areas which may explain the repetitive behaviours in OCD
- Orbitofrontal cortex (OFC) and thalamus: both believed to be overactive resulting in increased anxiety
3 strengths of biological explanations of OCD
- supporting evidence gives theory empirical weight
- the variation of OCD symptoms in different individuals can be explained by the genetic variations that may underline their disorder, therefore the explanation has good explanatory power
- implications for treatment: treatments based on the biological causes have some success meaning that the theory has real world application
Limitations to the genetic explanation of OCD
- twin studies: concordance rate isn’t 100%, must be other factors involved, explanation is oversimplified and reductionist - doesnt take into account other factors, like environment
- diathesis-stress model is able to explain the late onset found in some cases and therefore the cause is an interaction with the environment (isn’t entirely genetic)
- equal shared environment issue: twin studies assume that all twins share equal environments however MZ twins are more likely to share the exact same environment than DZ twins.
- the complexity of so many genes involved (230+) means the usefulness is reduced in terms of predictive value
Limitations to neural explanation of OCD
- direction of causation isn’t clear: can’t tell whether the neural differences have caused the OCD or the other way around or a 3rd factor caused both.
- serotonin link could be due to the co-morbidity of the disorder with depression (disruption of serotonin system could be due to the depression alongside OCD and not affect OCD at all)
HOWEVER - recent research has shown that antidepressants that treat depression but have no effect on levels of serotonin don’t have any effect on OCD, implying that serotonin is directly associated with OCD itself and not just the depression - effectiveness of SSRIs is only 50-80% indicating that there is likely to be another explanation alongside the neurotransmitter levels
- treatments may help improve symptoms but don’t address the cause
Name one study that researched the effectiveness of drug therapy on OCD
Soomro reviewed 17 studies comparing SSRIs to placebos in the treatment of OCD and concluded that all studies showed significantly better results for the SSRIs than placebos. For SSRIs, symptoms were significantly reduced by 70%
Explain Beck’s cognitive explanation for depression
- Beck proposed that depression is the result of maladaptive thinking processes (cognitions).
- the world is seen negatively through negative schemas which dominate thinking and are triggered when individuals are in situations similar to those where the schemas were learned
- negative schemas may have developed in childhood for example due to authority figures placing unrealistic demands on individuals. These schemas then continue into adulthood and produce a negative framework where people look at the world pessimistically.
- negative schemas and cognitive biases maintain the triad
- triad: the self, the world, the future
What are negative schemas and give one example?
Beliefs formed from past experiences that lead to expectations. E.g., self-blame schemas - makes the depressive feel responsible for all misfortunes
What are cognitive biases and give one example?
Faulty information processing that are fuelled by negative schemas (errors of thinking/errors of perception). e.g., focusing on negative aspects of a situation and ignoring any positives.
Name 1 study to support and contradict Beck’s cognitive explanation for depression
Support: Grazioli and Terry tested 65 pregnant women for cognitive vulnerabilities and found those who were more vulnerable were more likely to suffer from post-natal depression
Contradict: McIntosh and Fisher found no evidence for a clear separation of negative thoughts but instead a single one-dimensional negative perception of the self.
Explain Ellis’ cognitive explanation for depression
- ABC model, good mental health is the result of rational thinking. Depression results from irrational thought where the individual lames external event for their unhappiness.
- A (activating event) B (beliefs) C (consequences)
- ABC model predicts that people who think more irrationally should respond to daily stressors differently than to people who think less irrationally.
Name 1 study to support Ellis’ cognitive explanation for depression
Zeigler and Leslie found that students who scored higher on overall irrational thinking reported a significantly higher frequency of daily stressors than those who scored lower on irrational thinking. This indicates support for the ABC model.
What are SSRIs/what do they aim to do for OCD?
Selective serotonin reuptake inhibitors - given to OCD sufferers as it blocks the reabsorption of serotonin at the synapses, inhibiting reuptake and therefore increases levels of serotonin
They aim to reduce the anxiety caused by the obsessions, which will reduce the need for compulsions to be carried out