Psychiatry Drugs Flashcards
What is the benzodiazepine used in alcohol withdrawal?
Chlordiazepoxide
What is the fastest acting benzodiazepine?
How quick does this act?
Lorazepam
Orally 1 hour
IM 30 mins
What is the trade name for diazepam?
Valium
What neurotransmitter do benzodiazepines affect?
Do they enhance or inhibit?
GABA
Enhance it’s affect?
What are the therapeutic properties of benzodiazepines?
Sedative Anxiolytic Hypnotic (sleep inducing) Muscle relaxant Anticonvulsant
In a rapid tranquilization how much lorazepam would you give?
How much haloperidol?
1mg lorazepam
5mg haloperidol
What are the risks with taking benzodiazepines?
Respiratory depression
Hypotension
What are the general side effects of antipsychotics?
EPSE Weight gain Hyperprolactinaemia Anti cholinergics Postural hypertension Diabetes
How do atypical antipsychotics work?
Antagonise the dopamine pathways
How doss aripiprazole work?
dopamine parties agonist so has a different effect in meso cortical and mesolimbic areas
In schizophrenia what is the general management?
Orlanzepine (atypical) Then Zuclopenthioxol Then Clozapine Then augment clozapine
Max does of Orlanzepine?
And starting dose?
20 mg
Start on 5mg
Starting dose of clozapine?
Max dose?
12.5mg
Up to 200mg
How long does it take to titration clozapine up to its full dose?
2 weeks
If you miss a dose of clozapine what must happen?
Restart titration at 12.5mg