Psychiatry Flashcards
Management of moderate depression
1, Prescribe an SSRI
2. If ineffective for at least 2-4 weeks > check adherence 3. Increase the dose
4. Change to a different SSRI
5. Try alternative class of antidepressant (atypical antidepressants > Mirtazapine)
Antidepressants should usually show effect in
1-2 week
With good response to SSRIs >
Continue for at least 6 months after remission as this reduces relapse
Patients who had 2 or more depressive episodes in the recent past and who experienced significant functional impairment during episodes
Continue for 2 years
When stopping SSRIs, the dose should be
reduced overa 4-week period
If the patient stopped medications abruptly and experiencing delusions
Neuropsychiatric analysis
Hospital management for depression
- Admission to the psychiatric ward
- investigations
- Treatment with SSRIs or SNRIs
4, Augmentation with lithium with CBT - If nothing works > ECT
Reasons for hospital admission
Serious risk suicide
© Serious risk of harming others
© Significant self-neglect
* Severe depressive or psychotic symptoms
© Lack or breakdown of social support
© Initiation of Electroconvulsive therapy (ECT)
© Treatment-resistant depression (where inpatient monitoring may be helpful)
High mood alone in the question (no mention of low mode at all)
> Hypomania
Low mode alone in the question (no mention of high mode at all)
Depression
High mode and low mode (depression) (no matter time in between
Bipolar
High mode with hallucinations and delusions >
Mania
Risk factors for suicide
- Previous suicide attempts © Previous self-harm
- Depression and other mental health problems
- Alcohol and drug abuse
- Low socio-economic status
Classically, periods of prolonged and profound depression alternate with periods of excessively elevated and irritable mood, known as mania
Bipolar affective disorder (Manic depression)
Features of Bipolar affective disorder
(Manic depression)
Decreased need for sleep
Pressured speech
Increased libido
Reckless behavior without regard for consequences © Grandiosity
More talkative than usual
Treatment for Bipolar affective disorder (Manic depression)
Mood stabilizers
Antipsychotics
It is a mood stabilizer that despite problems with tolerability, it still remains the gold standard in the treatment for preventing recurrences in bipolar disorder.
Lithium
Primary agents of choice for the acute treatment of bipolar disorder (mania) after taking into account both efficacy and tolerability
Antipsychotics
What are the kinds of Mood stabilizers ?
Lithium,
Valproic acid,
Carbamazepine,
Lamotrigine
Points about lithium
Do NOT offer lithium to women who are planning a pregnancy or are currently pregnant, unless antipsychotic medication has not been effective
+ [fa woman taking lithium becomes pregnant consider stopping the drug gradually over4 weeks
- [fa woman continues taking lithium during pregnancy, check plasma lithium levels everyw4eeks, then weekly from the 36% week and adjust the lithium dose to maintain plasma lithium levels at a therapeutic
dose
Tetralogy of lithium
Ebstein anomaly of the heart
Floppy baby
Thyroid abnormalities
A lesser degree of mania with persistent mild elevation of mood and increased activity and energy
Hypomania
Abnormally elevated mood
Mania
Hallucinations or delusions
Mania