General Surgery Flashcards
Boundaries of Hesselbach’s Triangle
Medial: Rectus abdominis
Lateral: Inferior epigastric vessels
Inferior: Inguinal ligament
MR LI II
Contents of the inguinal canal:
Spermatic cord (round ligament) + llioinguinal nerve
This is medial to the inferior epigastric artery
Direct inguinal hernia
This is lateral to the inferior epigastric artery
Indirect inguinal hernia
are ABOVE and medial to the pubic tubercle
Inguinal hernias
BELOW and lateral
femoral hernias
has impulse on coughing
Inguinal hernias
are usually irreducible (due to the narrow femoral canal)
and cough impulses are rarely detectable
Femoral hernias
Only they can extend into the scrotum
Indirect inguinal hernias
Incarcerated:
fixed to the wall
Strangulated:
obstructed bl. supply
Femoral hernia
(NAVY VAN
Groin hernias differences
Breast Anatomy
Breast cancer
Invasive ductal carcinoma.
Other types are
classified as ‘Special Type
Invasive lobular carcinoma
Ductal carcinoma-in-situ (DCIS)
Lobular carcinoma-in-situ (LCIS)
This is the most common type of breast
cancer. been renamed ‘No Special Type (NST).
Invasive ductal carcinoma.
One of the predisposing factors:
40% lifetime risk of breast/ovarian cancer
BRCA1, BRCA2 genes
Other predisposing factors:
1st-degree relative premenopausal relative with breast cancer (e.g. mother)
Nulliparity, 1st pregnancy > 30 years (twice risk of women having 1st child < 25 years)
Early menarche, late menopause (risk increases with more menstrual cycles as the breast undergoes division and apoptosis, which increases the risk of genetic mutation and tumor formation)
Combined hormone replacement therapy (relative risk increase * 1.023/year of use), COCP
Past breast cancer
Not breastfeeding
ionizing radiation
p53 gene mutations
Obesity
Previous surgery for benign disease (more follow-up, scar hides lump)
Decreased risk
Early pregnancy
Longer time breastfeeding
Management of Breast Cancer
1) Surgery: Around two-thirds of tumors can be removed with a wide-local excision.
Mastectomy x
® Multifocal tumor e
® Central tumor
® Large lesion in small breast
® DCIS >4cm
Wide Local Excision
®Solitary lesion
® Peripheral tumor
® Small lesion in large breast
® DCIS<4cm
2) Radiotherapy: to reduce recurrence.
3) Hormonal therapy: when tumor cells have hormone receptors, it blocks the effects of the hormones such as estrogen. Tamoxifen in pre-menopausal, in post-menopausal, aromatase inhibitors such as anastrozole (side-effects of tamoxifen include an increased risk of endometrial cancer, venous thromboembolism and menopausal symptoms)
4) Biological therapy: Trastuzumab, useful for HER-2 positive. Noting that it cannot be used in cardiac patients
5) Chemotherapy
Invasive ductal carcinoma extending to the epithelium
Breast ca
(Invasive Intraductal)
In situ carcinoma involving the nipple epidermis
Paget’s disease of the breast
Well-circumscribed lump with clear margins and separate from the
surrounding fatty tissue, there’s overgrowth of fibrous and glandular
tissue
Fibroadenoma
Fibrosis + epitheliosis with cystic formation
FbroadnoCIS
Cystic formation with mild epithelial hyperplasia in ducts
Fibrocystic changes of the breast
Breast cancer screening
* Women aged 50-74 years are offered mammogram
every 2 years
Breast cancer screening
* In high risk group, mammogram would be offered annually from ages
40-69
Core biopsy =
tru-cut biopsy
Sentinel LN biopsy is done
staging
Triple assessment of the breast
- Clinical
- Radiology
- <35-= USG
- > 35 = Mammogram
3. FNAC
USG
is used in young patients instead of mammograms due to increased tissue density which reduces sensitivity and specificity of a mammography
There’re four instances in which prophylactic mastectomy is advised:
- Strong family history of breast cancer
- Presence of gene mutations (BRCA1 or BRCA2)
- Previous cancer in one breast
- Biopsies showing lobular carcinoma in situ and/ or atypical hyperplasia of the skin
Remember these are offered in cases in which patients has a strong family history and has genetic markers for the cancer
prophylactic bilateral mastectomies and prophylactic bilateral oophorectomies
Axillary lymph node clearance
Indications
+ Positive sentinel lymph node biopsy (SLNB)
* Invasive breast cancer
Common complications
Axillary lymph node clearance
Numbness around the scar and upper arm (can be permanent)
Lymphoedema (localized fluid retention and tissue swelling caused by a compromised lymphatic system)
Seroma (fluid collection at the site of operation)
Frozen shoulders
<30years
Often described as “breast mice’ as they are firm, discrete, non-
tender, highly mobile lumps
Fibroadenoma
Middle-aged women
Lumpy breasts which may be painful
Symptoms may worsen prior to menstruation
FibroadenoCIS (fibrocystic disease)
(Benign mammary dysplasia)
Breast cancer
Hard, irregular lump
There may be associated nipple inversion or skin tethering
Chronic eczematous changes (itching — erythema — scales — blood stained nipple discharge — inverted nipple)
Usually unilateral
Diagnosed by punch biopsy
Paget’s disease of the breast
Duct ectasia
Most common around the menopause
May present with a tender lump around the areola
® Green or brown nipple discharge
- Nipple retraction
® Associated with smoking
Duct papilloma
Hyperplastic lesions rather than malignant or premalignant
Most common cause of blood-stained nipple discharge
There could be skin changes
Breast abscess
More common in lactating women
Unilateral, red, hot tender and fluctuant swelling
May present with purulent nipple discharge
Fat necrosis
More common in obese women
May follow trivial or unnoticed trauma
Firm & solitary localized lump and usually painless
Skin around the lump may be red, bruised or dimpled
Rare and may mimic breast cancer so further investigation is always
warranted
Ductal fistula
Suggested by para-areolar discharge
May follow abscess drainage or incision, there may be history of a spontaneous rupture of inflammatory mass preceding the fistula
Managed by excision under antibiotic cover
Recurrence is common
may also develop around the breast tissue
Lipomas and sebaceous cysts
CYStic and CYClical
fibroadenoClS
Haemorrhoidal tissue is part of the normal anatomy which contributes to anal continence. These mucosal
vascular cushions are found in the left lateral, right posterior, and right anterior portions of the anal canal (3 o’clock, 7 o’clock, and 11 o’clock respectively). Hemorrhoids are said to exist when they become enlarged, congested and symptomatic
Haemorrhoids
Features of Haemorrhoids
+ Painless rectal bleeding = the most common symptom
- Pruritus
« Pain: intermittent and usually not significant unless piles are thrombosed
+ Soiling may occur with third- or fourth-degree piles
Types of Haemorrhoids
External
Internal
+ Originate below the dentate line (lower 1/3 of the anal canal)
« Prone to thrombosis, may be painful
External
« Originate above the dentate line (upper 2/3)
+ Do not generally cause pain
Internal
- Severe recurrent rectal shooting pain
in the absence of any rectal disease
® Usually oceurs at night, after bowl
action or following ejaculation
- Anxiety is an associated feature
Proctalgia fugax
Grading of internal haemorrhoids:
Cannot be reduced |
Grade IV
Grading of internal haemorrhoids:
Do not prolapse out of the anal canal
Grade |
Grading of internal haemorrhoids:
Prolapse on defecation but reduce spontaneously
Grade ll
Grading of internal haemorrhoids:
Can be manually reduced
Grade lll
Management:
Soften stools =
increase dietary fiber and fluid intake
Management:
To alleviate symptoms =>
topical local anesthetics and steroids may be used
Management:
Outpatient treatments =
Rubber band ligation is superior to injection sclerotherapy
Management:
reserved for large symptomatic haemorrhoids which do not respond to outpatient treatments
Surgery
Management:
Newer treatments:
Doppler guided hemorrhoidal artery ligation, stapled haemorrhoidopexy
« typically present with significant pain
« examination reveals a purplish, edematous, tender subcutaneous perianal mass
« if patient presents within 72 hours = referral should be considered for excision
« Otherwise patients can usually be managed conservatively with stool softeners, ice packs and analgesia
+ Symptoms usually settle within 10 days
Acutely thrombosed external haemorrhoids
- Exquisite pain with defecation FRESH blood streaks covering the stools
- The fear of pain is so intense they avoid bowel movements and get constipation
- They refuse PR exam = PR done under anesthesia
s Acute: <6 weeks, chronic > 6 weeks
Anal fissure
In Anal fistula:
if low-submucosal or simple =
Lay open (fistulotomy),
In Anal fistula:
if complex/high (cross internal and external sphincters) =
Seton suture (ligation of fistula tract)
Complex fistulas can NOT be laid open as it could result in
fecal incontinence
60% are adenocarcinoma that occurs at the head of the pancreas
Pancreatic cancer
Risk factors of Pancreatic cancer
- Smoking
- Alcohol is an indirect RF as it causes chronic pancreatitis and liver cirrhosis
- Diabetes
- Chronic pancreatitis
Features of Pancreatic cancer
- Head: - Obstructive jaundice = Dark urine, pale stool, pruritis.
- Maybe painless although 70% are associated with epigastric or LUQ pain radiating to the back.
- Body or Tail: Epigastric or LUQ pain radiating to the back, relieved by sitting forward
- Both: Anorexia, weight loss or atypical weight loss
- Migratory thrombophlebitis (Trousseau sign): felt as small lumps under the skin
Investigations
nonspecific investigation of Pancreatic cancer
CA19-9
What are the other investigation of Pancreatic cancer?
- Transabdominal US
« CT
Management of Pancreatic cancer?
- Whipple’s resection (Pancreaticoduodenectomy): considered when no metastasis.
- Side-effects :
dumping syndrome (a group of symptoms, including weakness, abdominal discomfort, and sometimes abnormally rapid bowel evacuation, occurring after meals in some patients who have undergone gastric surgery) and peptic ulcer disease - ERCP with stenting for palliation
Rare cancer of the bile duct
Cholangiocarcinoma
Features of Cholangiocarcinoma
- Jaundice
- RUQ pain
- Weight loss
Features of
- Jaundice
- RUQ pain
- Weight loss
Colorectal cancer:
Asymptomatic people with no personal /family hx of bowel cancer: iFOBT every 2 yearly (50-74)
Low risk
Colorectal cancer:
One first-degree relative with CRC dx <55 yrs: iFOBT every 2 yearly (40-49); then
colonoscopy every 5 years (50-74)
Moderate Risk
Colorectal cancer:
: At least THREE first-degree or second-degree relatives with CRC, with at least ONE relative
diagnosed > 55 yrs: iFOBT every 2 yearly (35-44); colonoscopy every 5 years (45-74)
High Risk
For all patients this should be given for at least 2.5 years commencing at 50 until 70 years of age are
recommended unless contraindicated.
Aspirin
more common than gastric ulcers, epigastric pain relieved by eating
Duodenal ulcers
epigastric pain worsened by eating
Gastric ulcers
Features of upper gastrointestinal hemorrhage may be seen (hematemesis, melena etc.)
Peptic ulcer disease