Psychiatry Flashcards
What 2 classification systems are used for psychiatric conditions?
- DSM5
- ICD10
What can you ask the patient to recall in an abbreviated mental test?
- Recall an address
- Age and DOB
- What time is it?
- What year is it?
- Dates of WW2
- Name of present monarch
- Count backwards from 20
What are the components of the Mental State Examination?
ASEPTIC:
Attitude
Appearance & Behaviour (body language, eye contact, rapport, facial expressions)
Speech (rate, rhyme, tone, volume)
Emotions (mood, affect)
Perceptions (dissociative symptoms, illusions and hallucinations)
Thoughts (stream, form, content)
Insight and compliance
Cognition (capacity)
What is the Biopsychosocial formulation?
Takes biological, psychological and social factors to form a diagnosis.
4P’s:
Predisposing factors
Precipitating factors
Perpetuating factors
Protective factors
Name 10 examples of psychosocial therapies
- Psychotherapy
- CBT
- Counselling
- Cognitive analytic therapy
- Interpersonal therapy
- Dialectic behaviour therapy
- Family therapy
- Counselling
- Psychodynamic Therapy
- Electro-convulsive Therapy
What is suicide?
Intentional self-inflicted death
How could you breakdown the components of thought?
Stream
Form
Content
What is deliberate self harm?
Intentional non-fatal self-inflicted harm
What is an Illusion?
Misperception of real external stimulus
What is a hallucination?
Disorder of perception
Perception experienced in absence of external stimuli
What are the 5 types of Hallucinations
Auditory
Visual
Olfactory
Gustatory
Tactile
What are the 5 subtypes of Hallucinations
Hypnogogic = on falling asleep
Hypnopompic = on waking up
Autoscopic = seeing oneself
Reflex = stimulation in one modality produces hallucination in other
Extracampine - hallucinations outside of sensory fields
Charles Bonnet = visual hallucinations associated with eye disease
What is a Delusion?
Disorder of thought
A belief that is:
1) Firmly held
2) Not affected by rational argument/evidence
3) Not a conventional belief
Name 8 types of Delusions
Persecutory (think someone is going to hurt them)
Grandiose (inflated self-importance e.g. I am God)
Reference (events/actions take on special significance to patient (e.g. black cars monitoring me)
Nihilistic (delusion of almost nothingness e.g. nothing in bank account)
Hypochrondriacal (firm belief they have a disease)
Guilt or worthlessness (has done something shameful based on an innocent error)
Control (controlled by an outside agency)
Possession of thoughts
State the 5 types of possession of thoughts
Thought Insertion
Thought Withdrawal (someone removing their thoughts)
Thought Broadcast
Thought Echo
Thought Block (can’t continue idea)
What is Psychosis?
Severe mental disorder in which thought and emotions are so impaired that contact is lost with external reality
What is an ‘over-valued idea’?
False or exaggerated belief beyond logic or reason
Define loosening of association
A lack of logical association between thoughts
What is perseveration?
Repetition
Describe dissociation
Disconnection from surroundings
What is depersonalisation?
Feelings of detachment from one’s own body
Describe derealisation
A sense of one’s surroundings lacking reality
What is Lilliputian?
Visual hallucinations of small animals
What is Formication?
Insects crawling on skin
What is Neurosis?
Mild mental illness involving symptoms of stress, but not a radical loss of touch with reality
What is passivity Phenomena?
Actions are controlled by someone else
What is catatonia?
Significantly excited/inhibited motor activity
What is psychomotor retardation?
Slowing of thoughts/movements
What is concrete thinking?
Lack of abstract thinking
Most commonly in Aspergers
What is Confabulation?
False accounts to fill gap in memory
Most commonly in Korsakoff
What is a Neologism?
New word formation (to them it seems like it fits)
What is Anhedonia?
Inability to experience pleasure
What is Akathisia?
Inner restlessness and always in motion (rocking)
What does the Mesolimbic pathway cause?
Positive symptoms
What does the Mesocortical pathway cause?
Negative symptoms
What is Echolalia?
Meaningless repetition of another persons spoken words
What is Incongruity of affect?
Emotional responses that don’t match the situation
What is flat affect?
No emotional expression
What is Mannerism?
Repeated involuntary movements
What is Belle indifference?
Lack of concern for implications of symptoms
What is Pharmacodynamics?
What the drug does to the body (receptor sensitivity or agonism/antagonism)
What is Pharmacokinetics?
What the body does to the drug: ADME
Absorption
Distribution
Metabolism
Elimination
What are examples of anti-depressants?
Selective Serotonin Reuptake Inhibitors (SSRIs):
- Fluoxetine
- Sertraline
Tricyclic Antidepressants:
- Amitriptyline
- Clomipramine
Serotonin-noradrenaline reuptake inhibitors (SNRIs):
Noradrenaline and specific serotonergic antidepressants (NASSAs):
Monoamine oxidase inhibitors (MAOIs)
What are 3 side-effects of SSRIs?
- Headache
- Nausea
- Insomnia
What are the causes of Serotonin syndrome?
SSRIs
MAOIs
Ecstasy
What is the clinical presentation of Serotonin syndrome?
INCREASED ACTIVITY:
- Clonus/myoclonus
- Hypereflexia
- Tremor
- Muscle rigidity
- Dilated pupils
- Autonomic dysfunction (tachycardia/ unstable BP)
What investigations would you perform for Serotonin Syndrome?
Similar to NMS:
- CK: elevated
- FBC: elevated WCC
- LFTs: deranged
- ABG: Metabolic acidosis
What is the management of serotonin syndrome?
Benzodiazepines
5HT-2a antagonist (Cyproheptidine)
Define Dependance
Cluster of physiological, behavioural and cognitive phenomena in which a substance takes on a higher priority than other behaviours that once had greater value
What are 10 risk factors for Dependance?
- Male
- Low standard of education
- Unemployment
- Younger age of usage
- Mental illness
- Peer pressure
- Low self esteem
- High stress
- FHx of alcoholism / substance addiction
- Genetics
What is the clinical presentation of dependence?
Compulsion to drink
Tolerance (need more to get same effect)
Difficulties controlling alcohol consumption
Physiological withdrawal
Neglect of alternatives to drinking
Persistent use of alcohol despite harm
How can you assess alcohol dependance?
CAGE (cut down, annoyed, guilt, eye-opener)
Audit
What does Tweak stand for in alcohol dependence?
Tolerance (>6 drinks = 2pts)
Worried (yes = 2pts)
Eye-opener = 1pt
Amnesia = 1pt
Cut down = 1pt
> 3 = problem with alcohol
How would you investigate alcohol dependence?
Raised MCV: macrocytic anaemia
Vitamin B12 + folate deficiency
Deranged LFTs: GGT, AST/ALT
Thrombocytopenia: reduced platelets
Breath test
Screening
How would you manage Alcohol dependance?
Acomprosate: reduces craving
Disulfiram: gives hangover SE if alcohol consumed
Naltrexone: reduces pleasure alcohol brings
Support groups
CBT
Motivational interviewing
What is the clinical presentation of alcohol withdrawal?
Tremors
Sweating
Nausea/vomiting
Sound sensitivity (hyperacusis)
Insomnia
Mood disturbance (anxiety, on edge, depression)
Autonomic hyperactivity (tachycardia, HTN, pyrexia and mydriasis (pupil dilation))
Seizures seen -(at 36hrs)
How would you manage alcohol withdrawal?
Chlordiazepoxide (Benzodiazepine)
IV Pabrinex 5 days (vitamin B+C)
Thiamine 100mg BD
Inpatient: e.g. seizures with medical assisted detox
What is Wernicke’s encephalopathy?
A neurological emergency resulting from thiamine deficiency (vit B1)
Acute, reversible stage
Triad:
1. Ophthalmoparesis with nystagmus
2. Ataxia
3. Confusion
What triad is found in Korsakoff’s Syndrome?
▪ Anterograde amnesia
▪ Confabulation
▪ Psychosis (Lilliputian/formication)
What is Wernicke’s–Korsakoff syndrome?
A combination of Wernicke’s encephalopathy and alcoholic Korsakoff syndrome.
Chronic, irreversible stage
Severe memory impairment
What is the clinical presentation of opiate intoxication?
Drowsy
Mood change
Bradycardia
HTN
Pupil constriction
Respiratory depression
Decreased body temperature
What is the clinical presentation of opiate withdrawal?
Muscle cramps
Low mood
Insomnia
Agitation
Diarrhoea
Shivering
Flu like symptoms
What is the treatment for Wernicke’s encephalopathy?
IV Pabrinex (high potency B1 replacement)
Chlordiazepoxide
Alcohol abstinence
What is the management of Opioid overdose/dependance?
IV/IM naloxone (rapid)
Opioid dependance: detoxification (4 weeks in residential/12weeks in community)
Methadone
Buprenorphrine
What are the complications of Opioid misuse?
Infection: sharing needles
VTE
Overdose: respiratory depression
Crime/prostitution
What is delirium?
An acute confusional state often with changes in consciousness
Medical emergency
Often reversible
What are the causes of delirium?
PINCH ME
Pain
Infection/Intoxication
Nutrition (vit deficiency: thiamine, B12, folate)
Constipation
Hypoxia/hydration
Medication/substance abuse (benzodiazepines, anticholinergics, opiates, anticonvulsants)
Environmental
What is the clinical presentation of delerium?
Inattention
Disorientated
Visual hallucinations
Paranoia
What are the 3 clinical syndromes seen in delirium?
1) Hypoactive
* Apathy
* Withdrawal
* Quiet confusion
* Easily missed (often misdiagnosed as depression)
2) Hyperactive
* Agitation
* Lack of co-operation
* Delusions
* Disorientation
* Confused with schizophrenia
3) Mixed
How can you differentiate delirium from dementia?
Delirium vs Dementia
Acute vs gradual
Outside of brain vs brain pathology
Can improve vs can’t improve
Inattention vs still alert
Impaired consciousness vs conscious
Fluctuating symptoms vs stable
Treatable vs untreatable