Psychedelics

Question 1

List uses of psychedelic agents

Answer 1

Shamanistic/ religious
Sensory and aesthetic enhancement
Self exploration/ interpersonal awareness
Enhanced creativity, problem solving
Psychological healing
Neuroscience research

Question 2

List adverse effects of psychedelics

Answer 2

acute panic reaction (bad trip)
psychosis lasting > 48 hours
nausea, vomiting with peyote and ayahuasca

Question 3

list investigational uses of psiocybin

Answer 3

advanced cancer, alcohol and other substance use disorders, cluster headaches

Question 4

____ and ___ receptors are thought to dimerize in order to cause cellular signaling and the behavioral response to psychedelic drugs

Answer 4

5-HT2A and mGlu2

Question 5

List the sources of DMT

Answer 5

hallucinogenic snuffs used in South America and Haiti

Ayahuasca tea

Question 6

List the sources and effects of psilocybin

Answer 6

“magic mushrooms” used by Aztecs, others

Produces changes in cognition, colorful visual patterns, altered perception of time, feelings of sacredness/ profundity

Question 7

List sources and effects of MDMA

Answer 7

Synthetic substance

entactogen, was used as an adjunct to psychotherapy, now under investigation for tx of PTSD

Question 8

List medically beneficial effects of cannabis

Answer 8

analgesic (esp neuropathic pain), antiemetic, antispastic, antiglaucoma, appetite stimulation

Question 9

_____ is a synthetic cannabinoid used to reduce pro-emetic signaling to the vomiting center and is effective in reducing vomiting and stimulating appetite

Answer 9

Nabilone