Psych Gap

Question 1

Atypical Antipsychotics

Answer 1

clozapine
olanzapine: higher risk of dyslipidemia and obesity
risperidone
quetiapine
amisulpride
aripiprazole: generally good side-effect profile, particularly for prolactin elevation

Question 2

Adverse effects of atypical antipsychotics

Answer 2

weight gain
clozapine is associated with agranulocytosis (see below)
hyperprolactinaemia

Question 3

Risk of developing schizophrenia
monozygotic twin has schizophrenia
parent has schizophrenia
sibling has schizophrenia
no relatives with schizophrenia

Answer 3

Risk of developing schizophrenia
monozygotic twin has schizophrenia = 50%
parent has schizophrenia = 10-15%
sibling has schizophrenia = 10%
no relatives with schizophrenia = 1%