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Yr 4C > Psych Drugs > Flashcards

Psych Drugs Flashcards

1
Q

Antidepressant indications

A

depression, anxiety, neuropathic pain, eating disorders

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2
Q

SSRIs (5)

A

citalopram/escitalopram, fluoxetine, sertraline, duloxetine, paroxetine

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3
Q

SSRI AEs

A

BOW SIGHSS - bleeding, orthostatic hypotension, weight gain, sexual dysfunction, GI upset, hyponatremia, sleep serotonin syndrome, sweating (+/- initial anxiety/agitation)

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4
Q

Citalopram - key info

A

SSSRI, key SE - QT prolongation

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5
Q

Fluoxetine - key info

A

SSRI, use for adolescents

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6
Q

Paroxetine - key info

A

SSRI, key SE - sexual dysfunction

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7
Q

Sertraline - key info

A

SSRI, commonly used (usu well-tolerated), key SE - GI symptoms

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8
Q

Duloxetine - key info

A

SSRI, best for back pain

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9
Q

SNRIs

A

Venlafaxine, SEs - same as SSRI + hypertension (not ortho hypotension), more effective than SSRI but more toxic (more SEs)

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10
Q

Mirtazapine

A

SE - +++weight gain, sedation

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11
Q

1st line antidepressants

A

SSRIs, SNRIs, mirtazapine

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12
Q

MAOIs

A

Moclobemide, doesn’t cause sexual dysfunction, SE - cheese reaction

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13
Q

TCAs

A

Amitriptyline, nortryptiline

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14
Q

TCA - AEs

A

anti-HAM, major C: anti-Histamine (sedation), anti-Adrenergic (orthostatic hypotension, tachycardia, arrhythmias), anti-Muscarinic (anti-SLUDGE), Convulsions, Coma, Cardiotoxicity (OD = lethal)

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15
Q

2nd line antidepressants

A

TCAs, MAOIs

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16
Q

Mood stablisers

A

Ind: bipolar, lithium & anti-epileptics (sodium valproate, carbamazepine)

17
Q

Lithium - AEs

A

6 Ts - thirst, thyroid, tremor (fine), tone (weakness), thinking, toxicity (GAIT - GI upset, Ataxia, Impair consciousness, Tremor (coarse)) + nephrotoxicity

18
Q

Lithium - monitoring

A

baseline + 6mnthly: lithium lvls (baseline + 8h after dose), PTH, UEC, eGFR, TFT

19
Q

Sodium valproate - AEs

A

Hepatotoxicity, thrombocytopenia, hair loss, teratogenic

20
Q

Carbamazepine - AEs

A

Agranulocytosis, aplastic anaemia, teratogenic, ataxia

21
Q

Typical/ first generation antipsychotics

A

Chlorpromazine, haloperidol, flupenthixol, zuclopenthixol

22
Q

Typical antipsychotics - AEs

A

More EPSE, less metabolic: SEA HOW - sedation, EPSE (parkinsonism, akathisia, dystonia, tardive dyskinesia), anticholinergics, hyperprolactinaemia, orthostatic hypotension, weight gain/metabolic

23
Q

Atypical/ second generation antipsychotics

A

Risperidone, olanzapine, quetiapine, aripiprazole, amisulpride, clozapine (less EPSE, more metabolic SEs + better for negative symptoms)

24
Q

Olanzapine - key info

A

2nd gen antipsychotic, key SE - weight gain (worst)

25
Q

Quetiapine - key info

A

2nd gen antipsychotic, key SEs - ++sedation, best in Parkinson’s disease

26
Q

Aripiprazole - key info

A

2nd gen antipsychotic, least sedating

27
Q

Depot antipsychotics

A

haloperidol, zuclopenthixol, olanzapine

Yr 4C (6 decks)

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