Paediatrics - General & Cardio Flashcards
Paeds systems review
BIGDAD
- Birth/ pregnancy
- Immunisations
- Growth
- Diet (input & output)
- Allergies
- Development
Adolescent systems review
HEADSS
- Housing/ home/ environment
- Education/ employment
- Activities
- Drugs
- Sexuality
- Suicide/depression
Denver development screening questions
Smiling (6wks) Turns to sound (6mnths) Sitting (9mnths) First words (18mnths) Walking (18mnths) Stairs (3yrs) 3 word sentences (3yrs)
Closure of foramen ovale
Usu in first few breaths (due to LA pressure increase due to breathing)
Closure of ductus arteriosus
Usu w/i first few hrs to days, often Day 2-3 (becomes ligamentum arteriosum)
- Prostaglandin – ‘PROPs’ open the ductus arteriosus (^pO2 lowers PGE2)
- Indomethacin (prostaglandin inhibitor) – ‘INvolutes’ the ductus arteriosus
DA connects pulmonary artery to descending aorta
Cyanotic congenital HD causes
5T + H
- Tetralogy of Fallot
- Transposition of great arteries
- Total anomalous pulmonary drainage
- Truncus arteriosus
- Tricuspid atresia
- Hypoplastic left heart
Cyanotic heart disease
<85% SaO2 - caused by not enough oxygenated blood reaching tissues/ too much deoxygenated blood reaching tissues
Usu R –> L shunt
Acyanotic congenital HD causes
4 'non-Ts' - ASD - VSD - AVSD (can have both acyanotic & cyanotic features) - PDA (Usu L --> R shunt)
Ductal dependent congenital HD
Circulation is dependent on a patent ductus arteriosus (PDA) to preserve systemic circulation (L) or pulmonary circulation e.g. TOF w pulmonary atresia or TGA
–> may rapidly decline on 2-3 Day due to closure of ductus arteriosus
TOF features
PROV
- Pulmonary stenosis
- RV hypertrophy
- Overriding aorta (sits directly over VSD instead of LV = blood from both ventricles)
- VSD
TOF risk factors
Downs syndrome ("fall DOWN a lot" due to tet spells) DiGeorge syndrome - chromosome 22 deletion ("Sir George di Fallot")
Onset of cyanosis wks/mnths after birth, difficulty feeding, failure to thrive, tet spells, harsh ejection systolic murmur over pulmonary area (identified w/i first 2mnths of life), clubbing
TOF
TOF murmur
harsh EJS over left sternal edge (pulmonary area)
Cyanotic child squats to avoid fainting
Tet spell in TOF (cyanotic for 15mins due to vasospasm, may lead to syncope, child often squats to increase venous return to heart, usu self-limiting but can lead to MI, stroke or death if untreated)
Boot-shaped heart on CXR (coeur-en-sabot)
TOF (“booted out of the TOF”)
Term baby presents w cyanosis & feeding difficulty at Day 2-3
TGA (usu ductal dependent according to Monash EMQs)
Early cyanosis, single S2, usu no murmur (may be flow murmur)
TGA
TGA features
switching of great vessels (aorta –> RV, pulmonary artery –> LV), only compatible w life if ASD, VSD or PDA
“Egg on a string” CXR
TGA (RV hypertrophy) NB: CXR may be normal in early life
TGA management
- Prostaglandin E1 (maintain PDA)
- Balloon atrial septostomy (temporary - buys time until surgery)
- Surgery - arterial switch operation (w/i 1st week of life)
Patent ductus arteriosus
failure of closure of ductus arteriosus by 1 month after expected due date (EDD)
L –> R shunt
PDA risk factors
prematurity, congenital rubella syndrome
premature child, bounding pulse, continuous murmur
PDA
- Many children asymptomatic for a long time
- If severe may lead to heart failure (FTT, tachypnoea, difficulty feeding)
Continuous machinery murmur under left clavicle
PDA (esp older children, may be more systolic in younger children)
PDA Management
- Indomethacin (prostaglandin synthetase inhibitor)
- NSAID
- If fails –> Fluid restrict & diuretics + surgery (coil impaction)
Wide, fixed splitting of S2 + mid-systolic/ejection systolic murmur at L sternal edge
ASD (NB: larger ASD = louder murmur)
Atrial septal defect features
Usu asymptomatic, mid-systolic/ ejection systolic murmur at L sternal edge on routine exam
Baby with Down Syndrome has poor feeding with difficulty breathing and sweating. He has a systolic murmur
AVSD (NB: may have cyanotic component)
Apical pansystolic murmur
AVSD (murmur due to AV valve regurg)
Most common congenital HD
VSD (~30%)
A 3 or 4 month old patient presents with poor weight gain, poor feeding, tachypnoea, and a loud systolic murmur heard across the entire praecordium
VSD
Sx of HF in infant
Failure to thrive, tachypnoea, tachycardia, difficulty feeding, excessive sweating, fatigue, SOB, enlarged liver, frequent chest infections, irritability, gallop murmur
Harsh apical pansystolic murmur + parasternal heave
VSD (NB: VSD murmur may spontaneously disappear)
–> louder murmur = smaller VSD (more turbulence)
Sx HF + pansystolic murmur
VSD
Patent foramen ovale
Failure of the foramen ovale to close after birth (normally closes w first breath), mostly asymptomatic
PFO risks
ischaemic stroke secondary to paradoxical embolism
Sudden change from acyanotic HD (ie ASD, VSD, PDA) to cyanotic HD
Eisenmenger’s syndrome (due to pulmonary HTN leading to reversal of L to R shunt, very poor prognosis, requires heart/lung transplant)
Prevention of Eisenmenger’s syndrome
Fix hole (VSD, ASD, PDA) before pulmonary HTN develops
Benign, musical/humming systolic murmur at left sternal border
Still’s murmur
Coartication of aorta
a congenital condition where the aorta narrows in the area where the ductus arteriosus inserts (–> severe obstruction to LV outflow), duct dependent
Coartication of aorta RFs
Turner’s syndrome
Asymptomatic at birth, cyanosis & shock at Day 2-3, absent femoral pulses, radio-femoral delay, higher BP in arms>legs, EJS murmur radiating to back (posterior left scapulae), severe HF
Coartication of aorta
Rib notching on CXR
Coartication of aorta
Congenital pulmonary stenosis RFs
Noonan syndrome
Alagille syndrome associations
TOF, pulmonary stenosis
Classic congenital HD associations
Down syndrome: AVSD (most common), Tetralogy of Fallot, VSD
Turner’s syndrome: Coarctation of aorta (pretty classic), Aortic stenosis (but coarctation more common)
Noonan syndrome: Pulmonary stenosis
Alagille syndrome: Pulmonary stenosis, TOF
Congenital rubella syndrome: PDA