Psych Flashcards

1
Q

small molecule transmitters

A

amino acids (NT)
monoamines (NM)
acetylcholine (NM)
NO

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2
Q

amino acid neurotransmitters

A

glutamate: excitatory
GABA: inhibitory

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3
Q

monoamines neuromodulators

A

catecholamines (NE/epi/dopamine)
serotonin
histamine

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4
Q

function of NE/epi

A

sympathetic, wakefullness, arousal, attention, memory

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5
Q

function of dopamine

A

reward/motivation and executive function/motor control

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6
Q

function of serotonin

A

wakefullness, cognition, mood, appetite

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7
Q

function of acetylcholine

A

acts on nicotinic and muscarinic receptors at neuromuscular junction to activate parasympathetic system

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8
Q

large molecule transmitters

A

neuropeptides

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9
Q

neuropeptides

A

substance P/tachykinins: pain perception
kisspeptin/tachykinins: reproductive function
orexin: wakefullness
proopiomelanocortin: feeding and metabolism
endogenous opioids
cannabinoids

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10
Q

GABA synthesis

A

from gultamate, using vitamin B6

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11
Q

function of glutamate

A

predominant excitatory NT of brain, expressed everywhere

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12
Q

receptor of glutamate

A

ionotropic (fast/excitatory)

GPCR (slow/inhibitory and excitatory)

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13
Q

clearance of glutamate

A

pre/post/glial cell uptake receptors

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14
Q

function of GABA

A

predominant inhibitory NT of brain, expressed everywhere

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15
Q

receptor of GABA

A

ionotropic and metabotropic

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16
Q

clearance of GABA

A

pre/glial cell uptake receptors

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17
Q

receptor for acetylcholine

A

ionotropic (nicotinic)

metabotropic (muscarinic)

18
Q

synthesis of acetylcholine

A

from acetyl CoA and choline

19
Q

location of acetylcholine expression

A

basal forebrain and brainstem

20
Q

clearance of acetylcholine

A

acetylcholine esterase

21
Q

location of NE expression

A

pons, brainstem

22
Q

location of epi expression

A

adrenals

23
Q

receptors for NE/epi

A

alpha1, alpha2, beta2 (heart)

24
Q

clearance of NE/epi

A

pre-synaptic autoreceptors

25
Q

formation of NE/epi

A

from tyrosine

26
Q

synthesis of dopamine

A

from tyrosine

27
Q

receptor for dopamine

A

GPCRs

G1=stimulation, G2=inhibition

28
Q

clearance of dopamine

A

DAT

29
Q

synthesis of seratonin

A

tryptophan

30
Q

receptors for seratonin

A

many! both ionotropic and metabotropic

31
Q

nucleii locations of seratonin

A

brain and gut

32
Q

clearance of seratonin

A

SERT (pre-synaptic)

33
Q

receptor for endophins

A

mu

34
Q

receptors for enkephalins

A

delta

35
Q

receptors for dyrnophins

A

kappa

36
Q

receptor for endomorphins

A

mu

37
Q

sensory aphasia (Wernicke)

A

inability to comprehend written or spoken words, some difficulty speaking

38
Q

motor aphasia (Broca)

A

non-fluent speech

39
Q

global aphasia

A

both Broca and Wernicke

40
Q

depersonalization

A

disorder of perception, feel dissociated from sensations

41
Q

psychoanalysis

A

promotes awareness of unconscious, maladaptive and habitually recurrent patterns of emotion and behavior

42
Q

supportive psychotherapy

A

reinforcement of patent’s healthy and adaptive patterns of thought. unlike psychoanalysis because the therapist is an encouraging, supportive team member.