PSY Flashcards
SSRI examples
Fluoxetine
Fluvoxamine
Sertraline
Escitalopram
Citalopram
ASEPTIC mnemonic for MSE
Appearance and Behavior
Speech
Emotions
Perceptions
Thought
Insight
Content
Special parts of a PSY hx
Past psychiatric history
Family hx of psy conditions
Social hx
Occupational hx
Substance use eg smoking,drugs
Educational hx
Psychosexual
O&G
Childhood
Premorbid personality
Drugs for treatment for MDD
Bio
SSRI
SNRIs
NaSSa
Augmentation:combination, ECT,Lithium,antipsychotics
PSY: CBT
Social: interventions
Diagnostic criteria for Major Depressive Disorder
5 or more of
- Depressed mood
- Sleep disturbance
- Anhedonia
- Feelings of worthlessness/guilt
- Fatigue
- Diminished cognition(pseudodementia)
- Weight change
- Psychomotor changes(agitation or retardation)
- Suicidal ideation
Medical causes to rule out in patient with depressive symptoms
Hypothyroidism
Cushings
Cancer
Myocardial infarct
Chronic disease eg SLE
Side effects and CIs of Lithium
SEs
Polyuria
Polydipsia
GI disturbance
Fine tremor
Renal ajd thyroid dysfunction
Encephalopathy
CIs
Pregnancy: causes Ebsteins abnormality
Breastfeeding
Sodium valproate SEs
Thrombocytopenia
Liver dysfunction
Teratogen:Neural tube defects in pregnancy
Lamotrigine for bipolar SEs
SJS and dermatological
Mood stabilisers
Valproate,Lithium,Lamotrigine
Best mood stabiliser for rapid cycling and cyclothymia
Sodium Valproate
Definition of rapid cycling
4 or more episodes of depression,mania or hypomania in a single year
Definition of cyclothymia
1.Periods of sx of depression and hypomania but do not meet criteria for either
2. >2years
3. Sx present >1/2 the time
4. Sx never absent for > 2/12
Definition of treatment resistant depression
Persistence of symptoms despite 2 or more treatment trials, including haloperidol and olanzapine
Drug of choice for Treatment resistant schizophrenia
Clozapine
Examples of SNRIs
Venlafaxine and desvenlafaxine
Example of NaSSa/ Noradrenergic Selective Serotonergic antidepressant
Mirtazipine
Sx of major depressive disorder
Low mood
Anhedonia
Feelings of guilt/worthlessness
Sleep disturbance(hypersonic or insomnia)
Weight and appetite changes
Lethargy
Cognitive changes/pseudodementia
Psychomotor changes
Suicidal ideation
SEs of typical antidepressants
Haloperidol: Extrapyramidal symptoms, hyperprolactinemia
Chlorpromazine: Dyslipidemia, Weight gain/T2DM, anticholinergic, orthostatic hypotension, QTC prolongation
Type of amnesia from ECT
Retrograde
Sx of PTSD mnemonic
TRAUMA
Traumatic event
Re experiencing
Avoidance
Unable to function
More than a month
Arousal increased
+-Derealization/Depersonalization
Mx of PTSD
- Trauma focused CBT
- EMDR(Eye movement desensitisation and reprocessing)
- Pharmacotherapy: SSRI,SNRI and prazosin