Psoriasis Flashcards
Psoriasis.
(1) A (CHRONIC/ACUTE), inflammatory disorder most commonly characterized by cutaneous erythematous plaques with silvery scale.
(2) It is a complex ______-mediated disorder associated with flares related to systemic, psychological, infectious, and environmental factors.
(3) Plaque (vulgaris): Most common variant (~80% of cases).
(4) Genetic predisposition (polygenic); 40% have psoriasis in a _______.
1) Chronic
2) Immune
3) first-degree relative
(1) Well-demarcated salmon pink-to-red erythematous papules and plaques; silvery scale.
(2) Distribution favors scalp, auricular conchal bowls, and postauricular area; extensor surface of extremities, especially knees and elbows; umbilicus, lower back, intergluteal cleft, and nails.
(3) Nail findings: Pitting, oil spots, onycholysis.
(4) Auspitz sign: Pinpoint bleeding with removal of scale.
(5) Koebner phenomenon: New psoriatic lesions arising at sites of skin injury/trauma.
(6) Genitals affected in up to 40% of patients.
Plaque Psoriasis
Treatment
(1) Topical
-(a) Adult initial therapy: medium-potency corticosteroids daily:
-(b) Topical retinoids:
(2) Systemic therapy
-(a) Patients with Psoriasis involving more than 20% of the body surface or who are very uncomfortable should consider systemic therapy.
(3) Phototherapy (light box Therapy)
-(a) Targeted exposure to UVR in dermatology.
Patients with Psoriasis involving more than 20% of the body surface or who are very uncomfortable should consider what type of therapy?
systemic therapy
What is Koebner phenomenon?
New psoriatic lesions arising at sites of skin injury/trauma
What is Auspitz sign
Pinpoint bleeding with removal of scale
Lab considerations for Psoriasis
KOH to rule of Tinea
Xrays for joint pain r/o psoriatic arthritis
Complications psoriasis
(1) Psoriatic arthritis
(2) Exfoliative dermatitisComplications
Disposition psoriasis
Routine referral to Dermatology for further evaluation and definitive treatment
