Psoriasis Flashcards

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1
Q

Define psoriasis

A

Chronic inflammatory skin disease, which has characteristic lesions & may be complicated by arthritis

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2
Q

Aetiology of psoriasis

2

A

UNKNOWN

Genetic, environmental & drugs are implicated

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3
Q

Risk factors for psoriasis

3

A

Guttate psoriasis - streptococcal sore throat
Palmoplantar psoriasis - smoking, middle aged women, autoimmune thyroid disease
Generalised pustular psoriasis - hypoparathyroidism

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4
Q

Epidemiology of psoriasis

prevalence, age

A

Affects 1-2% population

Peak age of onset 20 yrs

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5
Q

Presenting symptoms of psoriasis

3

A

Itching & occasionally tender skin
Pinpoint bleeding w/ removing scales (Auspitz phenomenon)
Skin lesions may develop at sites of trauma/scars (Koebner phenomenon)

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6
Q

Signs of psoriasis on physical examination

7 groups

A

Discoid/nummular psoriasis

Flexural psoriasis

Guttate psoriasis

Palmoplantar psoriasis

Generalised pustular psoriasis

Nail signs

Joint signs - 5 presentations of psoriatic arthritis

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7
Q

Signs of psoriasis on physical examination - discoid/nummular psoriasis

A

Symmetrical, well-demarcated erythematous plaques w/ silvery scales over extensor surfaces (e.g. knees, elbows, scalp, sacrum)

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8
Q

Signs of psoriasis on physical examination - flexural psoriasis

A

Less scaly plaques in axilla, groin, perianal & genital skin

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9
Q

Signs of psoriasis on physical examination - guttate psoriasis

A

Small drop like lesions over trunk & limbs

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10
Q

Signs of psoriasis on physical examination - palmoplantar psoriasis

A

Erythematous plaques w/ pustules on palms & soles

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11
Q

Signs of psoriasis on physical examination - generalised pustular psoriasis

A

Pustules distributed over limbs & torso

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12
Q

Signs of psoriasis on physical examination - nail

3

A

Pitting
Onycholysis
Subungual hyperkeratosis

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13
Q

Signs of psoriasis on physical examination - joint

5

A
5 presentations of psoriatic arthritis 
Asymmetrical oligoarthritis
Symmetrical polyarthritis 
Distal interphalangeal joint predominance 
Arthritis mutilans
Psoriatic spondylitis
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14
Q

Investigations for psoriasis

5

A

Most patients DO NOT need investigations

Guttate psoriasis - anti streptolysin-O titre, throat swab
Flexural psoriasis - skin swabs to exclude candidiasis
Nail clipping analysis for onychomycosis (fungal infection)
Joint involvement analysed by checking for rheumatoid factor & radiographs

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