Psoriasis Flashcards
Define psoriasis
Chronic inflammatory skin disease, which has characteristic lesions & may be complicated by arthritis
Aetiology of psoriasis
2
UNKNOWN
Genetic, environmental & drugs are implicated
Risk factors for psoriasis
3
Guttate psoriasis - streptococcal sore throat
Palmoplantar psoriasis - smoking, middle aged women, autoimmune thyroid disease
Generalised pustular psoriasis - hypoparathyroidism
Epidemiology of psoriasis
prevalence, age
Affects 1-2% population
Peak age of onset 20 yrs
Presenting symptoms of psoriasis
3
Itching & occasionally tender skin
Pinpoint bleeding w/ removing scales (Auspitz phenomenon)
Skin lesions may develop at sites of trauma/scars (Koebner phenomenon)
Signs of psoriasis on physical examination
7 groups
Discoid/nummular psoriasis
Flexural psoriasis
Guttate psoriasis
Palmoplantar psoriasis
Generalised pustular psoriasis
Nail signs
Joint signs - 5 presentations of psoriatic arthritis
Signs of psoriasis on physical examination - discoid/nummular psoriasis
Symmetrical, well-demarcated erythematous plaques w/ silvery scales over extensor surfaces (e.g. knees, elbows, scalp, sacrum)
Signs of psoriasis on physical examination - flexural psoriasis
Less scaly plaques in axilla, groin, perianal & genital skin
Signs of psoriasis on physical examination - guttate psoriasis
Small drop like lesions over trunk & limbs
Signs of psoriasis on physical examination - palmoplantar psoriasis
Erythematous plaques w/ pustules on palms & soles
Signs of psoriasis on physical examination - generalised pustular psoriasis
Pustules distributed over limbs & torso
Signs of psoriasis on physical examination - nail
3
Pitting
Onycholysis
Subungual hyperkeratosis
Signs of psoriasis on physical examination - joint
5
5 presentations of psoriatic arthritis Asymmetrical oligoarthritis Symmetrical polyarthritis Distal interphalangeal joint predominance Arthritis mutilans Psoriatic spondylitis
Investigations for psoriasis
5
Most patients DO NOT need investigations
Guttate psoriasis - anti streptolysin-O titre, throat swab
Flexural psoriasis - skin swabs to exclude candidiasis
Nail clipping analysis for onychomycosis (fungal infection)
Joint involvement analysed by checking for rheumatoid factor & radiographs