PSA Flashcards
1
Q
list 4 teratogenic anti-epileptics
A
sodium valporate
carbamazepine
phenobarbital
phenytoin
2
Q
list CYP450 enzyme inducers
A
PCBRASSS
Phenytoin
Carbamazepine
Barbituates
Rifampicin
Alcohol (chronic)
Smoking
St John’s wort
sulfonylureas (-ides)
(induce COCP)
3
Q
cytochrome P450 inhibitos
A
AODEVICES
allopurinol
omeprazole
disulfram
erythromycin
valporate
isoniazid
ciprofloxacin
ethanol (acute)
sulphonamides (abx)
4
Q
drugs requiring therapeutic drug monitoring (trough/ peak samples)
A
phenytoin
lithium
aminophylline
ciclosporin
digoxin
warfarin
tacrolimus
gentamicin
vancomycin
5
Q
which drugs reduce seizure threshold?
A
ciprofloxacin
nefopam
tramadol
lithium
anti-depressants
anti-psychotics
6
Q
what are the maintenance fluid requirements?
A
water 25-30ml/kg/day
Na+/K+/Cl- 1mmol/kg/day
glucose 50g-100g/ day
