Protozoaires Flashcards

1
Q

Les protozoaires

A

Eucaryote, unicellulaire

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Transmission malaria

A

Transmission anophèle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

les 5 types de plasmodium

A

P. Falciparum, P. vivax, P. ovale,P. knowlesi, P. Malariae)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Cycle exo-erythrocytique

A

1- mosquito takes blood meal and injects sporoxoite
2- infected liver cell
3- shizont dormant
4- Shizont rupture - goes to blood cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Cycle erythrocytique

A

5- shizont in blood cell
6- Shizont ruptures and goes multi-systeme of the body
or
6- Shizont creates gametocyte ingested my mosquito

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Sx de malaria

A

< 2 semaines (variable)
Non spécifique
Diarrhée, NoVo, céphalées, myalgies
Fièvre Tierce (48h) = Falciparum, vivax et ovale
Fièvre Quarte (72h) = malariae

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Tx contre le malaria

A

Falciparum = hospitalisation
USI si Sx sévère

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Loi 31 paludisme

A

Zone non résistance chloroquinone: chloroquinone, hydroxychloroquinone, méfloquine, atavoquane

Zone résistante C = Méfloquine, atavoquane et doxy

Zone résistance C et méfloquine = atavoquane et doxycycline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Les 8 traitements possibles pour la malaria

A

Quinine, chloroquine, hydroxychlorquine, atavoquane-preguanil, mefloquine, doxycycline, artemisine, primaquine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Les traitements en prophylaxie pour malaria

A

Tous sauf quinine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Types de plasmodium qui causent hypnozoïtes et Tx

A

P. Ovale, P. vivax

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Les 3 protozoaires intestinaux

A

Coccidies (intracellulaire, sporulation)
Amibes (vacuole contractile, pseudopode)
Flagellés

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Caractéristiques des coccidies

A

Intracellulaire
Infection entérocytes = diarrhée osmotique
Production spores

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Danger du C. parvum

A

Résistant au chlore
Faible dose infectieuses
Zoonose potentielle
Survie ad 12 mois eau froide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Mécanisme de transmission du C. Parvum

A

1- thick wall oocyst exists host
2- contamination water/food
Ingested by host

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Traitement C. parvum

A

Autorésolutif ou Nitazoxanide
Immunosupprimés: nitazoxanide ou paramomycine
Pas de baignade 2 semaines post-diarrhée

17
Q

Sx C. parvum

A

Diarrhée (incubation 7-10 jours, malabsorption)
20 % transmissible

18
Q

Nitazoxanide (Spectre, MA, E2)

A

Protozoaire: Cryptosporidum, Giardia
Helminthe:

Bloque métabolisme anaérobique
E2 = bien toléré, dlr abdo

19
Q

Paramomycine (Spectre, E2)

A

Cryptosporidum et E. hystolica
E2 = non absorbé

20
Q

Mécanisme de transmission E. Histolyca

A

1- Cyst/tophozoite in feces
2- MAture cyst ingested

21
Q

Sx et traitement E. Histolyca

A

Sx = ulcères, diarrhées muqueuses +/- sanglantes, extension sous-muqueuse ad extension
Dissémination foie, hématogène

Tx: toujours traiter
Ax = agent luminal (idoquinol, paramomycine)
Amibiase et abcès = métronidazole + agent luminal

22
Q

Iodoquinol (Spectre, E2)

A

E. Histolytica et D. Fragilise
E2 = Rash, névrite optique, NoVo

23
Q

Mécanisme de transmission du Giardia

A

Ingestion du Giardia via aliments contaminés

24
Q

Sx du Giardia

A

50% asymptomatique
Aigu = incubation 7-14j, diarrhée, stéatorrhée, NoVo, perte de poids pendant 2-4 semaines

Chronique = selles molles et malabsorption

25
Q

Tx du Giardia

A

1 Métronidazole, nitazoxanide

Éviter lactose 1 mois

26
Q

Les infections MADO

A

C.Parvu et E. histolytica

27
Q

Les infections MADO

A

C.Parvu et E. histolytica