protozoa Flashcards
What is a Protozoa
Eukaryotic single celled
5 major groups of Protozoa
Flagellates
Sporozoa
Amoebae
Microsporidia
Ciliates
Scientific name for sleeping sickness
African trypanosomiasis
Symptoms of visceral leishmania
Fever
Weight loss
Massive spleen
Most common type of amoebic disease
Amoebic dysentery
5 species of malaria
Plasmodium FALCIPARUM
Plasmodium ovale
Plasmodium vivax
Plasmodium malariae
Plasmodium knowlesi
Which gender spreads the malaria
Female
How to test for diagnosis of malaria
Blood film
Main symptoms of malaria
Chills
Fever
Headache
Myalgia
Fatigue
Diarrhoea
Vomiting
More advances symptoms of malaria
Anaemia
Jaundice
Hepatosplenomeganu
Main treatment for complicated malaria
IV artesunate
FEVER AND TRAVEL
Malaria
Basics of malaria
Vector is anopheles
Hose is humans and animals
Spread in blood
Infects liver and RBC
Some species can be dormant
Which two species of malaria can persist in humans long term without proper treatment
P malarie
P knowlesi
how does a human become infected by malaria
mosquito takes a blood meal and ingest gametocytes
mosquito injects human with sporozoites
infected liver cell
Chizont burst and offspring enters the blood stream
INFECT, PROLIFERATE and infect more red blood cells
how is p falciparum more severe
causes obstructed microcirculation
what is obstructed microcirculation
rbc puts out signals on membrane , rbc becomes sticky to the endothelial
rolling, rosetting, and block off small venules
cause vascular occlusion
obstructed microcirculation in brain can cause ?
vascular occlusion
obstructed microcirculation in kidney can cause ?
vascular occlusion
dehydration
hypotension
haemoglobinuria
haemolysis
complicated treatment of malaria
IV artesunate
which two species of malaria can become dormant and cause relapse
p vivax
p ovale
Most common cause of non falciparum malaria
p, vivax
Specific feature of p vivax
cyclical fever every 48 hrs
