funghi

Question 1

cell biology of funghi

Answer 1

eukaryotic
chitinous cell wall
heterophobic
move through spores

Question 2

yeast vs mould?

Answer 2

yeast- single celled that divides by budding
mould- tubular structure multicellular and form spores

Question 3

why doesn’t funghi usually cause human infection

Answer 3

inability to grow at 37 degrees
unable to evade innate and adaptive responses

Question 4

invasive fungal infection is rare or common

Answer 4

rare but easily missed

Question 5

very common type of fungal infection

Answer 5

superficial fungal infection

Question 6

common examples of funghal infections

Answer 6

nappy rash
athletes foot
fungal nail
fungal asthma

Question 7

where are the majority of costs going for antifungal treatmetns

Answer 7

150m a year
prophylaxis or empirical treatment of possible invasive fungal disease due to poor diagnostics

Question 8

4 methods of fungal diagnostics

Answer 8

radiology
microscopy
culture
molecular

Question 9

ideal diagnostic test should be ?

Answer 9

Non-invasive
Rapid and easy technically
Sensitive and reproducible
Specific – both in terms of pathogen, significance of positive result
Cheap

Question 10

common side effect with long term use of fluconazole

Answer 10

alopecia

Question 11

what is diamorphic funghi

Answer 11

grows as yeast in tissue and mould in-vitro

Question 12

most common type of yeast infection

Answer 12

candida albicans

Question 13

summary of aspergillus fumigatus

Answer 13

predominantly lung infections, allergic disease
poor prognosis but kills slowly