proto-oncogenes

Question 1

VEGF

Answer 1

F: growth factors
PROTEIN ENCODED: vascular endothelial gf
TUMOUR: kaposi’s sarcoma

Question 2

HER2

Answer 2

F:growth factor receptor
PROTEIN ENCODED: Human EGF receptor 2
TUMOUR: breast cancer

Question 3

KRAS

Answer 3

F:signal transduction
PROTEIN ENCODED: Rds protein
TUMOUR:colon adenocarcinoma

Question 4

MYC

Answer 4

F:transcriptional activators
PROTEIN ENCODED: c-MYC transcription factors
TUMOUR:small lung cancer, beta cell lymphoma

Question 5

CDK 4

Answer 5

F:regulators of cell cycle
PROTEIN ENCODED: cyclin dependent kinase 4
TUMOUR: melanoma,glioblastoma

Question 6

Cyclins

Answer 6

F:regulators of cell cycle
PROTEIN ENCODED:cyclin D protein
TUMOUR:mantle cell lymphoma,breast carcinoma