Proteins Structure & Function Pt.2

Question 1

Four types of secondary structures

Answer 1

*Alpha Helix
*Beta Sheet
Beta Turn
Omega Loop

Question 2

Secondary structures are formed by

Answer 2

hydrogen bonds between N-H and C=O groups

Question 3

Start the amino acid with the carbon with

Answer 3

a free amino group (N-term)

Question 4

The end of the amino acid is

Answer 4

the free carbon with the carboxyl group (C-term)

Question 5

Hydrogen bonds are formed between

Answer 5

H and electronegative atoms (Oxygen)

Question 6

Alpha helix are stabilized by

Answer 6

intrachain hydrogen bonds

Question 7

Beta strands form H bond two type of ways

Answer 7

Anti parallel and parallel

Question 8

What determines if a protein is polar and non-polar

Answer 8

The R group

Question 9

Folding is driven by the strong tendency of

Answer 9

hydrophobic (non-polar) amino acids to be excluded from water

Question 10

Polar molecules are mostly found in the

Answer 10

cytoplasm

Question 11

Unpaired N-H or C=O groups in peptides prefer

Answer 11

water (hydrophilic)

Question 12

What interactions with the side chain stabilize the structure

Answer 12

Van der Waals interactions

Question 13

Pairing the N-H or C=O groups with H bonds make them less

Answer 13

hydrophilic

Question 14

The simplest quaternary structure is a dimer consisting of

Answer 14

two identical polypeptide chains called subunits

Question 15

What determines if the polypeptide chain will form an alpha helix or a beta sheet

Answer 15

Amino acid residues

Question 16

Denaturation

Answer 16

loss of structural integrity with accompanying loss of activity

Question 17

Proteins can be denatured by

Answer 17

*Temperature
*pH extremes
* Organic solvents
*Chaotropic agents

Question 18

The sequence alone determines

Answer 18

the native conformation