Proteins: Primary and secondary structure Flashcards
What is the result of proteins having a unique shape?
They have different functions in organisms
What is a polypeptide?
A long chain of amino acids linked together
What determines the primary structure of the protein?
order of amino acids
how many naturally occurring amino acids are there? How many combination does that result in ?
20
Trillions of combinations
Are polypeptides always straight?
No, they can curl and fold into 2 main shapes:
- alpha-helices
- Beta pleated sheets
What is the meaning of helix?
Coil/Spring shaped
What causes the polypeptide shape variations to occur?
The structure of amino acids
How does alpha helix structure form?
polypeptide chain coils and the hydrogen bonds between oxygen and hydrogen keep the coil stable
How does the beta pleated sheet structure form?
polypeptide chains form a zig zag and fold over themselves
Since hydrogen bonds are weak, how do they keep the
secondary structures stable?
A single hydrogen bond is weak, but many hydrogen bonds collectively keep the secondary structure stable
Define secondary structure of a protein
It is the curling or folding of a polypeptide chain into alpha-helices or beta pleated sheets due to formation of hydrogen bonds