Proteins Flashcards
protein
proteios=first in rank (Greek), macromolecule built up by amino acids
structure of proteins
3D, spatial form of the protein chain stabilized by weak interactions (electrostatic, van der Waals)
primary structure of proteins
sequence of amino acids building up the molecule
secondary structure of proteins
formation of regular structures (α-helix, β-sheet) in the peptide chain stabilized by H-bonds
quaternary structure of proteins
spatial arrangement of peptide chains and non-peptide components of a protein
conformational change
transient, reversible change in the spatial structure of a protein molecule
globulin
protein molecule that has a spherical tertiary structure (e.g. hemoglobin, immunoglobulin)
myoglobin
iron-containing oxygen-binding protein molecule in the muscles resembling hemoglobin
denaturation
usually irreversible change in the conformation of protein molecules
antibody (and immunoglobulin)
protein molecule produced by the lymphocytes that can specifically bind to antigens
memory cell
lymphocyte specialized for the long-term storage of the code to synthesize an antibody
antigen
usually a large molecule or a smaller part of it that induces immunological response in the target organism
autoimmune disease
erroneous immune response of an organism against its own proteins or macromolecules
complement system
protein molecules responsible for the elimination of the antigen-antibody complex
effector protein
protein transmitting the effect of G-protein activation in the cell
G-protein
GTP-binding protein at the inner surface of plasma membranes; plays a critical role in signal transduction
glycoprotein
a protein containing carbohydrate groups
intrinsic (integral) protein
membrane protein spanning
peripheral (extrinsic) protein
protein associated to the external or internal surface of the cell membrane
the membrane from one surface to the other
lipoprotein
protein molecule containing lipid groups
peptide
short protein molecule
contractility
ability for shortening
actin and myosin
proteins responsible for the muscle contraction
filament
thin fiber made up of proteins; sliding of actin and myosin filaments on each other explains muscle contraction.
collagen
protein, main component of the collagen fibers
albumin
largest protein fraction in the blood plasma, mainly responsible for the colloid osmotic pressure of the plasma
fibrinogen
protein component of the blood plasma; its polymerization to fibrin is the most important step of blood coagulation