Atom(-bonds) Flashcards
alpha carbon atom
in organic acids the C-atom closest to the carboxyl group (see alpha-amino acids)
covalent bond
the strongest bond between two atoms in which electrons are shared on common molecular orbits
electronegativity
dimensionless number indicating the affinity of atoms of a given element to the electrons
hydrogen-bond
weak interaction between an H-atom bound to a highly electronegative atom (O, N) in a molecule and another highly electronegative atom (O, N) in the same or a different molecule
purines
compounds based on a two-ring structure containing five C and four N atoms; adenine and guanine, bases in nucleic acids are purine compounds
pyrimidines
compounds based on a ring containing four C and two N atoms; uracil, thymidine and cytosine, bases in nucleic acids are pyrimidine compounds
side chain
a group bond to the -carbon atom of amino acids; amino acids are distinguished by the chemical composition of this group
van der Waals forces
relatively weak attraction between atoms and molecules with hydrophobic properties due to the random fluctuation of the electron clouds
alpha helix
helical secondary structure of proteins stabilized by H-bonds between peptide bonds located above each other
beta sheet
two-dimensional secondary structure of proteins stabilized by H-bonds between peptide bonds on chain segments running in opposite directions
cis and trans position
on the same or on the opposite side (e.g. the two possibilities for the continuation of the lipid chain at the two ends of a double bond in an unsaturated fatty acid)
disulfide linkage
a bond between two sulfide groups (side chains of cystein amino acids) determining the structure of proteins
non-covalent bonds or weak forces
supplemental, but important interactions between and within biological molecules: electrostatic (ionic) bond, H-bond, van der Waals interaction
peptide bond
covalent bond created by condensation (reaction releasing a water molecule) of the amino and carboxyl group of two amino acids
secondary structure of proteins
formation of regular structures (α-helix, β-sheet) in the peptide chain stabilized by H-bonds