Proteins Flashcards

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1
Q

Proteins

A

-monomers are called amino acids
-amino acids are joined by peptide bonds
polymer- large molecules consisting of large numbers of repeating units connected by covalent bonds
monomer- a small molecule that may become chemically bonded to other monomers to form a polymer
amino acid= monomer
peptide= polymer

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2
Q

Function

A
  • catalysis
  • muscle contraction
  • transport of nutrients ad gases- proteins help with transport
  • cytoskeleton- gives animal cells shape
  • tensile strengthening- needed in skin, tendons, ligaments
  • blood clotting- plasma proteins
  • hormones- chemical messengers
  • receptors- binding sites for hormones
  • cell adhesion- causes cells to stick to each other
  • immunity- antibodies for immune systems
  • membrane transport - selective permeable
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3
Q

A
  • proteins vary in structure and function
  • each type has a unique 3 dimensional shape
  • amino acids are the building blocks of proteins
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4
Q

General Structure

A

R group
Amino Group
Carboxyl Group

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5
Q

different amino acids have different R groups. Their different properties depend on their R groups. Hydrophobic and hydrophilic R groups

A

human can synthesis some amino acids by altering other amino acids, however…
some amino acids cannot by synthesized and are therefore needed in the diet.

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6
Q

Formation of dipeptide produces a molecules of water, therefore… this is a condensation reaction

A

2 amino acids = dipeptide + water

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7
Q

formation of dipeptide

A

carboxyl group of one amino acid reacts with amino group of second amino acid

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8
Q

Hydrolysis Reaction

A

splitting a dipeptide to form two amino acids consumes one molecule of water

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9
Q

Tripeptide: three amino acids linked together
Oligopeptdie: a short chain of a few amino acids
Polypeptide: a chain of many amino acids

A

a protein consists of one or more polypeptide chains

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10
Q

Amino acids can be linked together in any sequence giving a huge range of possible polypeptides

A

…..

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11
Q

Proteins and Polypeptides

A
  • some proteins are single polypeptides but others are composed of 2 or more polypeptides linked together
  • integrin, collagen, hemoglobin
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12
Q

Lysozyme

A

enzyme in secretion such as nasal mucus and tears; it kills some bacteria by digesting the peptidoglycan in their cell walls

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13
Q

Integrin

A

membrane protein used to make connections between structures inside and outside in cells

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14
Q

Collagen

A

structural protein in tendons, ligaments, skin and blood vessel walls; it provides high tensile strength, with limited stretching

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15
Q

Hemoglobin

A

transport protein in red blood cells; it binds oxygen in the lungs and releases it in tissues with a reduced oxygen concentration

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16
Q

Protein Conformation

A
  • a protein function depends upon its specific conformation

- protein conformation is made of different levels of structure

17
Q

4 levels of protein structure

A

Primary- amino acid sequence (polypeptide)
Secondary- coiling of folding of proteins due to H bonding between amino and carbonyl groups of adjacent amino acids, alpha helixes and beta pleated sheets
Tertiary- H bonding between R groups of different amino acids. Disulfide linkages form
Quaternary- linking of 2 or more polypeptides to form a single protein, insulin and hemoglobin

18
Q

Fibrous vs. Globular

A
Fibrous
-elongated
-strong
-insoluble in water
-collagen, keratin
Globular
-spherical
-weak
-soluble in water
-hemoglobin, enzyme
19
Q

Denaturation

A
  • a process that alters a proteins conformation
  • excessive heat
  • chemical agents that disrupts hydrogen bonds, ionic bonds, and disulfide bridges
20
Q

A

the correlation between form and function in proteins is an emergent property

21
Q

Proteomes

A

all of the proteins produced by a cell, a tissue, or an organism