Proteins Flashcards

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1
Q

Are proteins polymers?

A

Yes, of amino acids.

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2
Q

How many types of amino acids are there?

A

20

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3
Q

Give examples of proteins.

A

Enzymes, antibodies, hormones, muscle is made up of protein, haemoglobin has a special type of protein

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4
Q

What determines the function of a protein?

A

The amino acids in the protein (type, number, order) and how the protein folds.

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5
Q

What is the structure of an amino acid?

A

R group, amino group (NH2), carboxyl group (COOH)

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6
Q

What type of reaction is needed for a peptide bond to be formed?

A

Condensation reaction

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7
Q

What is a peptide bond?

A

A bond formed from the condensation reaction between two amino acids, the NH2 and COOh group.

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8
Q

How is the peptide bond different from the glycosidic linkage?

A

It has an NH instead of O only.

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9
Q

What is a polypeptide?

A

Many amino acids joined together by peptide bonds in condensation reactions.

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10
Q

Where do the condensation reactions to form a protein take place?

A

In ribosomes.

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11
Q

What is the primary structure of a protein?

A

The order of the amino acids in a polypeptide.

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12
Q

Why is the shape of a protein important?

A

It determines the function of the protein.

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13
Q

What is the secondary structure of a protein?

A

The way that the polypeptide is folded: alpha helix or in a beta pleated sheet.

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14
Q

What is the tertiary structure of the protein?

A

Further folding of the polypeptide into its 3D shape. Intermolecular bonds that hold the shape together.

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15
Q

What is the quaternary structure of a protein?

A

Some proteins are made up of more than one polypeptide chain which stick together by intermolecular bonds.

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16
Q

What do alpha helix and beta pleated sheets hold their structure?

A

Because of the hydrogen bonds.

17
Q

Why does the folding of the polypeptide chain not fall apart?

A

Because of 4 types of intermolecular bonds.

18
Q

What are the 4 types of intermolecular bonds in a tertiary structure?

A

Hydrogen bonds, ionic bonds, hydrophobic interactions and disulfide bonds.

19
Q

Give examples of proteins that have a quaternary protein structure.

A

Haemoglobin and collagen.

20
Q

how many polypeptide chains is haemoglobin made up of?

A

4

21
Q

how many polypeptide chains is collagen made up of?

A

3

22
Q

How are the polypeptide chains in quaternary structure held together?

A

By the same intermolecular forces/bonds as in the tertiary structure.

23
Q

What are globular proteins?

A

Soluble proteins that are made up of chains which are folded in a compact structure.

24
Q

What do globular proteins play an important role in?

A

Metabolic reactions

25
Q

Give examples of globular proteins

A

Enzymes and haemoglobin

26
Q

What are fibrous proteins?

A

They are proteins made up of long molecules to form fibres. Several helices wound around each other to form strong fibres.

27
Q

Give an example of a fibrous protein.

A

Collagen