protein synthesis 2 Flashcards
carries genetic information from DNA in nucleus ▶️ribosomes in cytoplasm
mRNA: The Messenger
- second step of protein synthesis
- occurs in ribosomes - protein factories of cell
Translation: Decoding the Message
changes specific patterns of gene expression in cells, consistent with changes that can __________?
lead to cancer
- causes anemia and other hematologic phenotypes
- defects in growth and development
- congenital anomalies, such as craniofacial defects and thumb
ribosome malfunction
- building blocks of proteins
- linked together by peptide bonds to form a polypeptide chain.
amino acid
sequence of amino acid determines protein’s…:
- structure
- function
can consist of 1 or more polypeptide chains
protein
misfolded proteins can lead to diseases such as:
Alzheimer’s, Parkinson’s
Proteins often undergo modifications after translation to become fully functional.
Post-Translational Modifications
can affect protein’s location, activity, & interactions with other molecules
modification
- changes in DNA sequence that can affect protein synthesis
- alter an organism’s appearance, behavior, and physiology, affecting all aspects of life, are crucial for evolution and genetic variation.
mutations
allows for production of proteins
genetic engineering
used to produce genetically modified organisms (GMOs)
Recombinant DNA technology