Protein structure Flashcards

1
Q

what is the primary structure

A

The sequence of amino acids

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2
Q

what is the secondary structure

A

The folding or coiling of an amino acid chain, due to hydrogen bonding.
Forms a a-helix or a B-pleated sheet

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3
Q

what is the tertiary structure

A

3D shape of the molecule, has a very precise shape

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4
Q

what is the quaternary structure

A

when a protein consists of more than one polypeptide chain

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5
Q

What part of a cell determines the primary structure

A

DNA, nucleus

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6
Q

Describe the alpha helix

A

held by H bonds
Amino acids per 10 turns of the helix

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7
Q

describe the b-pleated sheet

A

chains fold slightly in a zig zag structure

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8
Q

In the a-helix and b-pleated sheet, what parts of the amino acid do the hydrogen bonds bind to

A

The hydrogen bonds are between the amine group (-NH2) and the carboxyl group (-COOH) of another amino acid

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9
Q

What bonds are involved in the primary structure

A

Only peptide bonds

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10
Q

What bonds are used in the secondary structure

A

Peptide
Hydrogen

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11
Q

What bonds are used in the tertiary structure

A

Peptide
Disulphide
hydrogen
ionic
hydrophobic interactions

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12
Q

How does hydrophobic interactions make the amino acid spiral

A

The hydrophobic R groups associate with the centre of the polypeptide chain to avoid water exposure.
Hydrophilic parts of the amino acid are found at the edge of the polypeptide

Interactions of both cause amino acid chain to spiral

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13
Q
A
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