Protein Metabolism Study Flashcards

1
Q

What is the average protein content in a 70kg male?

A

10-12kg of protein

This represents 60-75% of protein within skeletal muscle.

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2
Q

What role do proteins play in the body?

A

Unique roles within a cell

Examples include enzymes, structural components, transport, hormones, immunology, and regulatory functions.

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3
Q

What are the building blocks of proteins?

A

Amino Acids

Amino acids are linked by peptide bonds.

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4
Q

How many amino acids are there?

A

20 amino acids

9 are essential and 11 are non-essential.

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5
Q

What are essential amino acids?

A

Amino acids that must be consumed

They include histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, and valine.

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6
Q

What are non-essential amino acids?

A

Amino acids that can be synthesized in the body

Examples include alanine, arginine, asparagine, aspartate, cysteine, glutamate, glutamine, glycine, proline, serine, and tyrosine.

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7
Q

What is protein turnover?

A

A continual state of turnover of proteins

This involves synthesis of new proteins and degradation of old ones.

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8
Q

What enzymes are involved in protein digestion?

A

Pepsin, Trypsin, Chymotrypsin, Carboxypeptidase, Elastase

Pepsin acts in the stomach; others act in the small intestine.

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9
Q

What is the free amino acid pool composition?

A

Glutamate 60%, Glutamine 14%, Alanine 4%

This pool is crucial for amino acid metabolism.

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10
Q

What is the primary energy source for the body?

A

Not considered primary energy source

Proteins are primarily used for energy during fasting or low energy intake.

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11
Q

What is the role of the TCA Cycle in amino acid metabolism?

A

Involves deamination or transamination

Amino acids enter the TCA cycle for energy metabolism.

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12
Q

What is deamination?

A

Removal of amino group as ammonia

Ammonia is converted to urea for excretion.

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13
Q

What percentage of nitrogen is excreted in urea?

A

90% of nitrogen

Ammonia is converted to urea to mitigate toxicity.

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14
Q

Fill in the blank: The amino acid pool in the body consists of _______ and _______.

A

free amino acids and protein reserves

This pool is essential for various metabolic processes.

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15
Q

True or False: All proteins in the body are synthesized from essential amino acids only.

A

False

Non-essential amino acids can also be synthesized from other amino acids.

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