Protein Metabolism Study Flashcards
What is the average protein content in a 70kg male?
10-12kg of protein
This represents 60-75% of protein within skeletal muscle.
What role do proteins play in the body?
Unique roles within a cell
Examples include enzymes, structural components, transport, hormones, immunology, and regulatory functions.
What are the building blocks of proteins?
Amino Acids
Amino acids are linked by peptide bonds.
How many amino acids are there?
20 amino acids
9 are essential and 11 are non-essential.
What are essential amino acids?
Amino acids that must be consumed
They include histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, and valine.
What are non-essential amino acids?
Amino acids that can be synthesized in the body
Examples include alanine, arginine, asparagine, aspartate, cysteine, glutamate, glutamine, glycine, proline, serine, and tyrosine.
What is protein turnover?
A continual state of turnover of proteins
This involves synthesis of new proteins and degradation of old ones.
What enzymes are involved in protein digestion?
Pepsin, Trypsin, Chymotrypsin, Carboxypeptidase, Elastase
Pepsin acts in the stomach; others act in the small intestine.
What is the free amino acid pool composition?
Glutamate 60%, Glutamine 14%, Alanine 4%
This pool is crucial for amino acid metabolism.
What is the primary energy source for the body?
Not considered primary energy source
Proteins are primarily used for energy during fasting or low energy intake.
What is the role of the TCA Cycle in amino acid metabolism?
Involves deamination or transamination
Amino acids enter the TCA cycle for energy metabolism.
What is deamination?
Removal of amino group as ammonia
Ammonia is converted to urea for excretion.
What percentage of nitrogen is excreted in urea?
90% of nitrogen
Ammonia is converted to urea to mitigate toxicity.
Fill in the blank: The amino acid pool in the body consists of _______ and _______.
free amino acids and protein reserves
This pool is essential for various metabolic processes.
True or False: All proteins in the body are synthesized from essential amino acids only.
False
Non-essential amino acids can also be synthesized from other amino acids.