Protein Folding

Question 1

The goal is to acheive_______ energy state!

Answer 1

LOWEST

Question 2

1.) The primary driving force for tertiary structures is?

Answer 2

HYDROPHOBIC DOMAINS

Question 3

2.) Folded protein looses in conformational ______.

Folding is Favorable for solvent entropy from burying hydrophobic groups.

Answer 3

ENTROPY

Hydrophobic Effect- (cluster hydrophobic R groups inside core)—> Clathrate structure

And Hydrophilic R groups line up outside the protein

Question 4

3.) What stabilizes INTERACTIONS between regions of polypeptides chains?

Answer 4

Hydrogen bonding

Secondary stuructures have H-bonding to stabilize the peotide backbone