Protein chemistry Flashcards
Functions of proteins
Provide nutrition, and nitrogen to the body. Act as a control mechanism for hormones and genetic expression, and modifies the cohesiveness, viscosity and
Acid/base proteins
amino groups: low pka’s- with proton
carboxyl groups: High pka’s-without proton
Protein is always charged regardless of pka and sometimes it exists at a pka of neutral charge because both charges cancel each other out.
Hydrocarbons
Glycine-tiny chain which is very rotatable and makes the entire protein very rotatable
Proline-contain an aromatic ring which is very difficult to rotate and it limits the number of conformations the protein can have.
Aromatic
Tryptophan
Theonine
phenoalaninine
Very non polar and hydrophobic
Polar
Hydroxyls-contain a hydroxyl group
amide-contain amine group and H bonding ability is very powerful
sulfyhydral group-cysteinse can connect to other cysteine molecules with a disulfide bond
Charged-
Acid base dissociation
ratio of products and reactants are forever constant
Henderson hasselback equation function
one unit above and below pka creates a 10 fold increase in positive ions or negative ions on the protein molecule depending on the direction being taken.