Prostate Path Flashcards
Acute Bacterial Prostatitis - Clinical Sx?
- Fever and chills
- Low back & perineal pain
- Irritative urinary tract symptoms (frequency, urgency and dysuria)
Acute Bacterial Prostatitis - Rectal Exam?
Swollen, boggy and tender prostate
Acute Bacterial Prostatitis - Urine cultures?
positive (usually gram-negative, E coli most common) and leukocytosis (≥ 10 WBCs/HPF)
Acute Bacterial Prostatitis - Tx?
Antibiotics
biopsy or resection not indicated
Chronic Bacterial Prostatitis - Clinical Sx?
- Recurrent UTI (cystitis, urethritis)
- Low back & perineal pain
- Mild irritative symptoms (frequency, urgency and dysuria)
Chronic Bacterial Prostatitis - Rectal Exam?
Swollen and boggy
Chronic Bacterial Prostatitis - Urine Cultures?
positive (usually gram-negative, E coli most common)
≥10 WBCs/HPF
Chronic Bacterial Prostatitis - Tx?
Antibiotics
biopsy or resection not indicated
Non-bacterial Prostatitis - Clinical Sx?
- Frequency, urgency, perineal pain and dysuria
- No recurrent urinary tract infection
Non-bacterial Prostatitis - Rectal Exam
May be normal
Non-bacterial Prostatitis - Urine cultures?
Negative (occasionally may find mycoplasma, chlamydia et al.)
≥ 10 WBCs/HPF
Non-bacterial Prostatitis - Tx?
Oxybutynin
Nonspecific Granulomatous Prostatitis - Clinical Sx & Demographics?
- Obstructive symptoms
- Recurrent infections
- Age 50-70 year old
Nonspecific Granulomatous Prostatitis - Rectal Exam?
- Nodular and hard
- suspicious of carcinoma.
Nonspecific Granulomatous Prostatitis - Pathogenesis?
Related to duct obstruction with accumulation of secretions, rupture, and tissue response to the leaked material; often associated with hyperplasia
What type of Prostatitis?
Mixture of histocytes, lymphocytes, plasma cells, eosinophils, neutrophils, and giant cells arranged in sheets without formation of discrete granulomas
Nonspecific Granulomatous Prostatitis
Post-Transurethral Resection Granulomatous Prostatitis - Clinical Sx?
- May be found up to 5 years following transurethral resection
- No clinical significant
What type of Prostatitis?
- Resemble rheumatoid nodules.
- Central zone of fibrinoid necrosis
Post-Transurethral Resection Granulomatous Prostatitis
What type of Prostatitis?
- Rim of palisaded epithelioid histocytes.
- Variable numbers of multinucleated giant cells
Post-Transurethral Resection Granulomatous Prostatitis
Post-BCG therapy Granulomatous Prostatitis - Clinical Sx?
Fever, mild hematuria and urinary frequency
Post-BCG therapy Granulomatous Prostatitis - Exam findings?
- 40% of patients with abnormal rectal exam
- 55% with ultrasonographic abnormalities
- PSA↑- Lesions mimic carcinoma
What type of Prostatitis?
- Diffuse, discrete granulomas
- With or without caseating necrosis
- Acid-fast bacilli can be identified (rarely
Post-BCG therapy Granulomatous Prostatitis
